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Tobacco Control 2002;11:119-124
© 2002 Tobacco Control


REVIEW

The genetics of tobacco use: methods, findings and policy implications

W Hall1, P Madden2, M Lynskey2

1 Office of Public Policy and Ethics, Institute for Molecular Bioscience, University of Queensland, St Lucia, Queensland 4072, Australia
2 Missouri Alcoholism Research Center, Department of Psychiatry, Washington University School of Medicine, 40 N Kingshighway, Suite One, St Louis, MO 63108, USA

Correspondence to:
Wayne Hall, Office of Public Policy and Ethics, Institute for Molecular Bioscience, University of Queensland, St Lucia, Queensland 4072, Australia;
W.Hall{at}imb.uq.edu.au


ABSTRACT
Research on the genetics of smoking has increased our understanding of nicotine dependence, and it is likely to illuminate the mechanisms by which cigarette smoking adversely effects the health of smokers. Given recent advances in molecular biology, including the completion of the draft sequence of the human genome, interest has now turned to identifying gene markers that predict a heightened risk of using tobacco and developing nicotine dependence


Keywords: genetics; tobacco use; policy; adoption studies; twin studies; linkage studies; nicotine dependence




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