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Luke Joseph Peppone, Kenneth M Piazza, Martin C. Mahoney, Gary R Morrow, Karen Mustian, Oxana G Palesh, Andrew Hyland
Associations Between Adult and Childhood Secondhand Smoke Exposures with Fecundity and Fetal Loss Among Women who Visited a Cancer Hospital
Tob Control 2008; 0: tc.2008.027961v1 [Abstract]
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[Read eLetter] This may be due to Low DHEA
James M. Howard   (21 December 2008)

This may be due to Low DHEA 21 December 2008
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James M. Howard,
Biologist
independent

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Re: This may be due to Low DHEA

jmhoward{at}anthropogeny.com James M. Howard

It is known that smoking increases DHEAS, the precursor of DHEA. The same should happen because of exposure to secondhand smoke.

DHEA is the active molecule, so increases in DHEAS may indicate that smoking is reducing DHEA. DHEA is known to be important to normal pregnancy-associated outcomes.

I suggest the findings of Peppone, et al., may be explained by reduced DHEA in these women.