Levels of toxins in oral tobacco products in the UK

Tob Control. 2006 Feb;15(1):64-7. doi: 10.1136/tc.2005.013011.

Abstract

Objective: This study examined the constituents of smokeless tobacco products available in the UK and compared them with products available in India, Sweden, and the USA.

Methods: Seven UK brands of smokeless tobacco, including a tooth cleaning powder, and four international brands of smokeless tobacco were tested for a range of toxins and known carcinogens, such as tobacco specific N-nitrosamines (TSNA), as well as nicotine availability.

Results: Ten of the 11 brands tested had detectable levels of tobacco specific nitrosamines, which are proven carcinogens, and levels varied 130-fold. All had detectable levels of benzo(a)pyrene, another proven carcinogen (with around 175-fold variation) and several toxic metals (with nearly 150-fold variation). Nicotine availability varied in the UK products from 0.1 mg/g to 63.2 mg/g. All the tobacco products tested are likely to be hazardous to users' health, but the data indicate that it should be possible to reduce key toxins to non-detectable levels.

Conclusions: Smokeless tobacco products should be regulated and standards set for maximum levels of toxins and carcinogens.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asia / ethnology
  • Benzo(a)pyrene / analysis
  • Biological Availability
  • Carcinogens / analysis*
  • Humans
  • Metals, Heavy / analysis
  • Nicotine / pharmacokinetics
  • Nitrosamines / analysis
  • Tobacco, Smokeless / chemistry*
  • United Kingdom

Substances

  • Carcinogens
  • Metals, Heavy
  • Nitrosamines
  • Benzo(a)pyrene
  • Nicotine