Comparisons of the main effects of Eclipse and Nicotrol inhaler
| Mean values (SE; range) | p Value1-150 | ||||
|---|---|---|---|---|---|
| Baseline | Eclipse | Inhaler | |||
| Cigarettes per day | 19.1 (1.0; 7–31) | 2.1 (0.5; 0–12) | 4.8 (0.7; 0–18) | 0.001 | |
| Carbon monoxide (ppm) | 21.0 (1.0; 8–34) | 33.0 (2.3; 14–66) | 12.7 (1.5; 2–42) | 0.001 | |
| Nicotine (ng/ml) | 16.8 (1.0; 6.6–33.3) | 18.0 (1.5; 6.1–51.3) | 12.2 (1.5; 0.8–47.1) | 0.001 | |
| Cotinine (ng/ml) | 330 (15; 157–622) | 312 (19; 138–679) | 259 (17; 57–480) | 0.001 | |
| Craving | 2.3 (0.2; 0–4) | 1.9 (0.2; 0–4) | 2.1 (0.1; 0–4) | 0.18 | |
| Missing cigarettes | 0.4 (0.2; 0–3) | 1.5 (0.2; 0–4) | 2.2 (0.2; 0–4) | 0.001 | |
| Other withdrawal symptoms | 0.6 (0.1; 0–2.1) | 0.5 (0.1; 0–2.6) | 0.7 (0.1; 0–1.9) | 0.01 | |
| Motivation to quit | 5.4 (0.4; 1.5–9.6) | 6.8 (0.4; 1.6–9.9) | 5.9 (0.4; 0.6–9.8) | 0.02 | |
| Heart rate | 76.3 (1.6; 60–100) | 76.0 (1.2; 60–96) | 73.7 (1.5; 52–95) | 0.05 | |
| Give up in 6 months | 47% | 68% | 72% | 0.47 | |
↵1-150 Eclipse versus inhaler.