Nicotine concentration and major flavouring chemicals identified in flavoured ENDS refill solutions used in this study
| Flavour brand name | Labelled nicotine concentration (mg/mL) | Determined nicotine concentration (mg/mL) | Identified flavouring chemicals | CAS Registry Number | Class |
|---|---|---|---|---|---|
| Tobacco | 24 | 23.0 | 3-Methylcyclopentane-1,2-dione | 765-70-8 | Diketone |
| (E)-β-damascone | 23726-91-2 | Ketone | |||
| Piña Colada | 24 | 22.5 | Allyl-cyclohexylpropanoate | 2705-87-5 | Ester |
| Methyl 3-hydroxyhexanoate | 21188-58-9 | Ester | |||
| Menthol | 24 | 22.0 | Menthol | 1490-04-6 | Alcohol |
| Limonene | 138-86-3 | Monoterpene | |||
| Carvone | 99-49-0 | Terpenoid | |||
| Coffee | 24 | 21.8 | 5-Methyl-2-phenylhex-2-enal (Cocal) | 4927-36-0 | Aldehyde |
| Strawberry | 24 | 22.5 | Benzyl alcohol | 100-51-6 | Alcohol |
| γ-Decalactone | 706-14-9 | Cyclic ester | |||
| Methyl cinnamate | 1754-62-7 | Ester |
ENDS, electronic nicotine delivery systems; PG, propylene glycol.