Abstract
The cost-effectiveness of smoking cessation interventions is well documented. However, most studies are based on randomized controlled trials (RCTs) and provide little information on the differences between subgroups. This study assessed the relative cost-effectiveness of smoking cessation interventions offered to various subgroups of smokers, based on real-life data. Regression analyses provided information on the factors determining abstinence and costs and led to the formation of relevant subgroups of smokers. Probabilistic Markov modeling was then used to estimate the relative cost-effectiveness of smoking cessation interventions for the entire database population and for the subgroups compared to a no-intervention case. The ICER for the base case population was estimated at €1,358. This is consistent with results from the existing literature. Group simulations showed lower ICERs for men, hospitals, and light smokers and falling ICERs with increasing age. Despite differences in the cost-effectiveness ratios between subgroups our results do not justify any kind of subgroup differentiation in a smoking prevention policy.
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Acknowledgements
T.E., H.M., H.H.J., and H.H. designed the data collection in collaboration with the other members of the Danish National Smoking Cessation Database (DNSCD) Steering Committee. M.R. handled the DNSCD data collection. H.H.J. drafted the design of the economic analysis. L.B. carried out the literature review and collected, with assistance from N.T.K., model parameters from other sources than the DNSCD. K.R.O. designed and carried out the modeling and data analysis with assistance from L.B.. L.B. and K.R..O. drafted the manuscript with assistance from H.H.J., and all authors critically reviewed and finally approved the manuscript. The study was supported financially by the Danish Ministry of the Interior and Health, The Danish Institute for Health Services Research and the Clinical Unit of Health Promotion at Bispebjerg Hospital. We thank statistician Andreas Habicht for data management assistance and Susanne Reindahl Rasmussen from DSI for helpful discussions on the analysis. An earlier version of the manuscript was presented at the 2005 IHEA Conference, and we thank the session participants for their interest in the analysis.
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Olsen, K.R., Bilde, L., Juhl, H.H. et al. Cost-effectiveness of the Danish smoking cessation interventions. Eur J Health Econ 7, 255–264 (2006). https://doi.org/10.1007/s10198-006-0362-1
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DOI: https://doi.org/10.1007/s10198-006-0362-1