Elsevier

Toxicology Letters

Volume 35, Issue 1, January 1987, Pages 117-124
Toxicology Letters

Gaschromatographic determination of polycyclic aromatic hydrocarbons, aza-arenes, aromatic amines in the particle and vapor phase of mainstream and sidestream smoke of cigarettes

https://doi.org/10.1016/0378-4274(87)90095-6Get rights and content

Abstract

Summery (1) The present arrangement collects particles and semivolatiles of main- and sidestream smoke and allows a recovery of the trapped substances nearly quantitatively and without impurities.

  1. 1.

    (2) The fractionation procedure allows to separate various groups of carcinogens such as PAH, azaarenes and aromatic amines for analytical and biological studies.

  2. 2.

    (3) Sidestream smoke contains ten times more polycyclic aromatic hydrocarbons (PAH) compared with mainstream smoke. This holds also true for aza-arenes and amines.

  3. 3.

    (4) PAH of the gaseous phases include only 1% of the particle-bound PAH.

References (1)

  • Tobacco Smoking

    IARC-Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans

    (1985)

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Invited paper, presented at the International Experimental Toxicology Symposium on Passive Smoking, October 23–25, 1986, Essen (F.R.G.).

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