Clinical and laboratory observationUrine cotinine excretion in neonates exposed to tobacco smoke products in utero
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Cited by (50)
Use of a physiologically-based pharmacokinetic model to explore the potential disparity in nicotine disposition between adult and adolescent nonhuman primates
2020, Toxicology and Applied PharmacologyCitation Excerpt :The terminal elimination half-life of plasma nicotine is about 2 h in adult humans (Matta et al., 2007). Urinary clearance rates (half-lives) of cotinine in newborns whose mothers smoked tobacco have been reported (Etzel et al., 1985; Dempsey et al., 2000). In other studies, infants and youth were exposed to second hand smoke, then placed in a smoke-free environment before urine collection, and the urinary clearance of cotinine was calculated from the collected samples (Collier et al., 1994; Leong et al., 1998).
Effects of Smoking Exposure in Infants on Gastroesophageal Reflux as a Function of the Sleep–Wakefulness State
2018, Journal of PediatricsCitation Excerpt :In infants from nonsmoking mothers, paternal smoking was the most significantly related determinant of measurable levels of urinary cotinine. In neonates, Etzel et al found an averaged cotinine half-life of 68 hours (range: 37-160 hours), whereas Leong et al found a median half-life of 28.3 hours (range: 6-259 hours) in infants.60,61 In the present study, our assay's limit of detection (1 ng/mL) enabled us to measure any exposure to nicotine.
Interpersonal and temporal variability of urinary cotinine in elderly subjects
2011, International Journal of Hygiene and Environmental HealthCitation Excerpt :The urinary cotinine levels of smokers have been shown to be consistent over 8 weeks (Murphy et al., 2004). Additionally, data using sequential measurements of urinary cotinine have been reported for neonates (Etzel et al., 1985). The average of multiple cotinine measurements should provide the best estimate of smoking and SHS exposure over a defined observation period.
Cigarette smoking during pregnancy: Chromosome translocations and phenotypic susceptibility in mothers and newborns
2010, Mutation Research - Genetic Toxicology and Environmental MutagenesisSimultaneous determination of nicotine, cotinine, norcotinine, and trans-3′-hydroxycotinine in human oral fluid using solid phase extraction and gas chromatography-mass spectrometry
2005, Journal of Chromatography B: Analytical Technologies in the Biomedical and Life SciencesControl of breathing in infants born to smoking mothers
1999, Journal of Pediatrics