Targeting interleukin-6 in inflammatory autoimmune diseases and cancers

X Yao, J Huang, H Zhong, N Shen, R Faggioni… - Pharmacology & …, 2014 - Elsevier
Abstract Interleukin-6 (IL-6) is a pleiotropic cytokine with significant functions in the
regulation of the immune system. As a potent pro-inflammatory cytokine, IL-6 plays a pivotal …

Posttreatment surveillance and diagnosis of recurrence in women with gynecologic malignancies: Society of Gynecologic Oncologists recommendations

R Salani, FJ Backes, MFK Fung… - American journal of …, 2011 - Elsevier
Although gynecologic cancers account for only 10% of all new cancer cases in women,
these cancers account for 20% of all female cancer survivors. Improvements in cancer care …

Regulatory and autoregulatory physiological dysfunction as a primary characteristic of post concussion syndrome: implications for treatment

JJ Leddy, K Kozlowski, M Fung… - …, 2007 - content.iospress.com
Although most patients with concussion recover within days to weeks, a small but significant
minority develop persistent signs and symptoms of post-concussion syndrome (PCS). The …

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

PD Kwong, ML Doyle, DJ Casper, C Cicala, SA Leavitt… - Nature, 2002 - nature.com
The ability of human immunodeficiency virus (HIV-1) to persist and cause AIDS is dependent
on its avoidance of antibody-mediated neutralization. The virus elicits abundant, envelope …

Essential role of the C5a receptor in E coli–induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation

TE Mollnes, OL Brekke, M Fung, H Fure… - Blood, The Journal …, 2002 - ashpublications.org
Complement plays an essential role in inflammation and tissue damage. However, it is
largely unknown to what extent the system acts as a primary inducer of secondary mediator …

Financial development and economic growth: convergence or divergence?

MK Fung - Journal of international money and finance, 2009 - Elsevier
This study tests for convergence in financial development and economic growth by
incorporating the interaction between the real and financial sectors into an otherwise …

Human ovarian cancer and cisplatin resistance: possible role of inhibitor of apoptosis proteins

J Li, Q Feng, JM Kim, D Schneiderman, P Liston… - …, 2001 - academic.oup.com
The inhibitor of apoptosis proteins (IAPs) constitutes a family of highly conserved apoptosis
suppressor proteins that were originally identified in baculoviruses. Although IAP homologs …

Productivity changes in Chinese airports 1995–2004

MKY Fung, KKH Wan, Y Van Hui, JS Law - Transportation Research Part E …, 2008 - Elsevier
This paper reports a study of the patterns of productivity changes in 25 regional airports in
China during the period 1995–2004. We found the average annual growth in airport …

Role for the alternative complement pathway in ischemia/reperfusion injury

GL Stahl, Y Xu, L Hao, M Miller, JA Buras… - The American journal of …, 2003 - Elsevier
The terminal complement components play an important role in mediating tissue injury after
ischemia and reperfusion (I/R) injury in rats and mice. However, the specific complement …

Strategies targeting the IL-4/IL-13 axes in disease

RD May, M Fung - Cytokine, 2015 - Elsevier
Abstract IL-4 and IL-13 are pleiotropic Th2 cytokines produced by a wide variety of different
cell types and responsible for a broad range of biology and functions. Physiologically, Th2 …