Migration to clean nicotine or dual use?

As more consumer-acceptable nicotine delivery systems emerge, advocates for the parallel availability of alternative sources of nicotine assume that there will be wholesale movement away from cigarettes. Yet, drift to such alternative products will rely on radical shifts in consumer demand in contexts where cigarettes will remain concurrently available. Importantly here, no nation has announced a future ban on combustible tobacco (talk of smokefree nations remains aspirational statements of hope) and no tobacco company has announced a wind-down in cigarette production, nor desisted from virulent opposition to policies that reduce smoking. A conclusion is unavoidable that the industry hopes to capitalise on harm-reduction sentiment by orchestrating the attainment of a richly rewarding dual use goal. Here, many smokers would continue smoking (highly profitable) cigarettes in all circumstances where this was possible, while also using non-combustible products in smokefree contexts (see figure 1). This would renormalise tobacco product use across the day previously characterised by large swathes of time where nicotine was not being used.

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Figure 1

Promotion of dual use in South Africa, 2006.

The investment advisors, Citigroup, are clear on the potential for dual use: ‘The [retail] trade believes that snus will be consumed in addition to cigarettes. Given the increased bans on smoking, snus products seem like an obvious substitution’.6 sentiments echoed in the US retail trade newsletter Brandweek: ‘There's money to be made from municipal smoking bans as another cigarette maker chases after smokers who get their nicotine fix between their cheek and gum during those many moments when they can't light up’.7 When harm-reduced products carry the same brand names as cigarettes, the potential for mutual reinforcement is obvious.

There is evidence that substantial dual use is already occurring.8 ,9 Harm reduction advocates argue that this is best understood as a transitory phase toward exclusive harm-reduced product use or, eventually, cessation of all nicotine products, but the tobacco industry would have other ideas. Of all alternative nicotine delivery systems, e-cigarettes (note the category description) which involve traditional cigarette flavours (eg. classic tobacco and menthol), a glowing light-emitting diode (LED) tip evoking cigarettes, an exhalable vapour and frequent public display of the hand-to-mouth, theatrically semiotic exhaling and cigarette gesticulating ‘smoking performance’, seem most likely to risk cuing and reinforcing the attractions of smoking cigarettes. These very cigarette-like factors that make them more attractive to some smokers than other alternative forms of nicotine delivery (gum, patch, inhaler) combine in the über-cool ‘look at me, I'm smoking!’ public display, which is part of the attraction for young people to cigarette smoking. Social events and clubs set up explicitly for vaping are becoming common (Google returned 5630 hits for ‘vaping club’ on 6 December 2012), while nicotine patch or gum clubs are unheard of. E-cigarettes have seen advertising for smoking return to US television for the first time in decades (see cigarette manufacturer Lorillard's Blu here http://www.youtube.com/watch?v=VZishwAt_RM with its laughable caveat ‘Viewers of this video and all blu videos must be 18 years of age or older’ and ‘reclaim the night for freedom’ battle cry.

We consider it naïve to imagine that the tobacco industry would ever voluntarily take steps to reduce combustible tobacco use for as long as it remained highly profitable. If the industry's goal of dual use was achieved, this could be a harm-increasing outcome when assessed against the status quo of ever-declining smoking prevalence. Providing and encouraging access to highly addictive ‘clean nicotine’ products in smoking downtimes will sustain blood nicotine levels that will also be readily satisfied with cigarettes at times when these can be consumed. With the industry intent on promoting dual use, such a scenario may risk stalling the decline in smoking, as it has long been known that smokefree workplaces promote not only decreased consumption but cessation.10 ,11

Historical amnesia about pre-nicotine replacement therapy cessation

The assumption that it is somehow necessary to have an alternative ‘clean’ nicotine safety net for quitters is repudiated by decades of real-world evidence involving hundreds of millions of ex-smokers globally who did not require such a pathway out of smoking. Smoking prevalence began declining from the early 1960s in most anglophone nations some 20 years before nicotine replacement therapy (NRT) became available by prescription and then over the counter. The declines generally commenced later and proceeded more slowly in other nations. Between 1965 and 1987 in the USA, the proportion of ex-smokers to ever-smokers (the quit ratio) grew from 29.6% to 44.8%. In university graduates, it grew from 39.7% to a remarkable 61.4%.12 The American Cancer Society estimated in 1986—26 years ago—that ‘over 90% of the estimated 37 million people who have stopped smoking in this country since the Surgeon General's first report linking smoking to cancer have done so unaided’.13

Those insisting that it is somehow obvious that non-combusted nicotine should be an essential accompaniment to mass cessation seem to have either forgotten or are ignorant of the history of how this massive phenomenon occurred: for 25 years, in the absence of NRT, and thereafter, largely in spite of its increased availability.14 Even today, despite 20 years of massive marketing efforts by pharmaceutical companies and the dominance of assisted cessation within the smoking cessation community,15 in the USA, unassisted cessation today produces 2.8 times more successful quit attempts than are attributable to NRT.16

The seductive power of the hardening hypothesis

Data on smoking in 50 US states for 2006–2007 indicate that the mean number of cigarettes smoked daily, the percentage of cigarette smokers who smoke within 30 min of waking, and the percentage who smoke daily are all significantly lower in states with low smoking prevalence.17 Further, there has been a dramatic decline in heavy smoking in the USA.18 This is compelling evidence against the hardening hypothesis which would predict exactly the opposite. Australian data also show that the proportion of smokers with mental health problems has not increased in a decade when smoking prevalence continued to fall.19 Recent reviews and commentaries have concluded there is no evidence of hardening in the general population.20 ,21

Yet, the hardening hypothesis remains a stubborn subtext beneath many futuristic scenarios, invoking notions of an ever-desperate heavily addicted smoking population impervious to population-wide policies and programs and who, therefore, will need a clean nicotine safety net.