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Contributors AY conceptualised and developed the first draft. PL and SG contributed to the idea and critically reviewed different versions of the manuscript. All authors contributed to the revision and final manuscript in its present form.
Funding This work was supported by National Cancer Institute grant CA-087472; the funding agency played no role in the conduct of the research or preparation of the manuscript.
Competing interests No, there are no competing interests.
Patient consent for publication Not required.
Provenance and peer review Not commissioned; externally peer reviewed.
Data availability statement All data relevant to the study are included in the article.
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