Pharmacokinetics and pharmacodynamics of moist snuff in humans

Reginald V Fant; Jack E Henningfield; Richard A Nelson; Wallace B Pickworth

doi:10.1136/tc.8.4.387

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Original article

Pharmacokinetics and pharmacodynamics of moist snuff in humans

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Online download statistics by month: January 2000 to September 2024

	Abstract	Full	Pdf
Jan 2000	26	65	24
Feb 2000	37	430	15
Mar 2000	13	461	5
Apr 2000	3	295	1
May 2000	4	184	1
Jun 2000	6	126	0
Jul 2000	7	157	3
Aug 2000	6	173	0
Sep 2000	8	141	1
Oct 2000	3	210	1
Nov 2000	9	131	1
Dec 2000	5	182	0
Jan 2001	11	127	0
Feb 2001	14	197	4
Mar 2001	7	185	0
Apr 2001	13	233	0
May 2001	7	161	0
Jun 2001	40	251	3
Jul 2001	5	179	0
Aug 2001	6	181	3
Sep 2001	11	128	0
Oct 2001	3	140	4
Nov 2001	6	108	3
Dec 2001	3	89	1
Jan 2002	8	176	4
Feb 2002	7	156	1
Mar 2002	5	168	0
Apr 2002	8	245	0
May 2002	13	235	5
Jun 2002	13	155	6
Jul 2002	11	163	9
Aug 2002	10	144	10
Sep 2002	10	127	10
Oct 2002	5	121	5
Nov 2002	10	228	12
Dec 2002	5	169	5
Jan 2003	6	233	17
Feb 2003	15	110	10
Mar 2003	6	117	12
Apr 2003	3	111	4
May 2003	3	169	37
Jun 2003	14	229	9
Jul 2003	25	180	4
Aug 2003	30	188	8
Sep 2003	20	331	9
Oct 2003	24	339	3
Nov 2003	21	357	18
Dec 2003	18	325	10
Jan 2004	36	350	4
Feb 2004	40	529	10
Mar 2004	81	660	24
Apr 2004	75	607	24
May 2004	74	539	35
Jun 2004	106	479	21
Jul 2004	117	589	28
Aug 2004	123	618	36
Sep 2004	110	886	40
Oct 2004	88	958	30
Nov 2004	62	894	33
Dec 2004	74	675	23
Jan 2005	80	576	73
Feb 2005	62	461	31
Mar 2005	66	321	30
Apr 2005	29	229	16
May 2005	46	243	36
Jun 2005	26	197	17
Jul 2005	29	310	12
Aug 2005	33	591	18
Sep 2005	49	410	17
Oct 2005	40	416	29
Nov 2005	32	418	14
Dec 2005	24	365	23
Jan 2006	62	501	32
Feb 2006	26	378	16
Mar 2006	26	378	29
Apr 2006	31	322	33
May 2006	35	344	24
Jun 2006	26	336	28
Jul 2006	27	310	15
Aug 2006	48	392	25
Sep 2006	33	385	34
Oct 2006	36	342	30
Nov 2006	51	307	31
Dec 2006	27	247	30
Jan 2007	37	357	25
Feb 2007	41	302	32
Mar 2007	38	324	39
Apr 2007	190	35	8
May 2007	187	33	17
Jun 2007	162	21	7
Jul 2007	125	50	21
Aug 2007	144	25	12
Sep 2007	112	25	5
Oct 2007	131	41	13
Nov 2007	139	19	7
Dec 2007	103	19	6
Jan 2008	136	25	6
Feb 2008	132	20	9
Mar 2008	127	15	15
Apr 2008	141	12	12
May 2008	77	13	3
Jun 2008	93	14	13
Jul 2008	73	9	4
Aug 2008	93	16	5
Sep 2008	91	8	3
Oct 2008	105	17	4
Nov 2008	85	9	5
Dec 2008	84	17	6
Jan 2009	109	20	9
Feb 2009	81	13	8
Mar 2009	66	10	6
Apr 2009	52	11	7
May 2009	49	11	4
Jun 2009	88	12	2
Jul 2009	80	11	3
Aug 2009	77	9	2
Sep 2009	70	4	3
Oct 2009	70	15	11
Nov 2009	105	11	7
Dec 2009	43	5	6
Jan 2010	62	5	3
Feb 2010	65	9	6
Mar 2010	63	20	8
Apr 2010	58	14	4
May 2010	47	9	2
Jun 2010	37	8	5
Jul 2010	42	12	4
Aug 2010	53	22	7
Sep 2010	39	14	3
Oct 2010	53	9	5
Nov 2010	52	7	4
Dec 2010	28	4	1
Jan 2011	38	7	5
Feb 2011	23	20	5
Mar 2011	30	5	6
Apr 2011	18	7	2
May 2011	27	7	5
Jun 2011	16	7	3
Jul 2011	26	4	0
Aug 2011	23	6	2
Sep 2011	30	7	4
Oct 2011	43	8	4
Nov 2011	37	28	5
Dec 2011	21	54	6
Jan 2012	20	74	1
Feb 2012	17	59	2
Mar 2012	18	66	3
Apr 2012	16	66	6
May 2012	45	111	4
Jun 2012	48	95	6
Jul 2012	500	162	12
Aug 2012	524	165	38
Sep 2012	624	591	65
Oct 2012	677	694	78
Nov 2012	124	280	76
Dec 2012	114	208	71
Jan 2013	83	165	65
Feb 2013	18	98	10
Mar 2013	22	107	23
Apr 2013	25	114	14
May 2013	31	103	15
Jun 2013	9	102	10
Jul 2013	14	105	10
Aug 2013	24	151	5
Sep 2013	20	184	10
Oct 2013	15	175	17
Nov 2013	14	158	4
Dec 2013	9	239	7
Jan 2014	14	171	10
Feb 2014	28	123	4
Mar 2014	23	181	2
Apr 2014	19	185	17
May 2014	15	216	5
Jun 2014	14	174	6
Jul 2014	14	182	8
Aug 2014	15	197	10
Sep 2014	19	195	5
Oct 2014	13	148	1
Nov 2014	23	80	4
Dec 2014	8	97	6
Jan 2015	20	108	101
Feb 2015	5	82	156
Mar 2015	25	142	99
Apr 2015	11	76	50
May 2015	19	110	52
Jun 2015	14	107	44
Jul 2015	14	89	4
Aug 2015	23	100	5
Sep 2015	19	161	2
Oct 2015	15	58	5
Nov 2015	21	94	4
Dec 2015	27	98	6
Jan 2016	33	66	6
Feb 2016	21	50	4
Mar 2016	23	60	11
Apr 2016	22	156	7
May 2016	9	92	10
Jun 2016	4	102	6
Jul 2016	9	60	7
Aug 2016	39	62	9
Sep 2016	16	76	13
Oct 2016	30	77	14
Nov 2016	15	57	15
Dec 2016	17	54	15
Jan 2017	29	46	12
Feb 2017	12	41	15
Mar 2017	3	44	10
Apr 2017	9	79	5
May 2017	8	105	0
Jun 2017	13	56	5
Jul 2017	30	30	3
Aug 2017	86	81	11
Sep 2017	85	83	5
Oct 2017	87	69	1
Nov 2017	78	66	6
Dec 2017	81	77	3
Jan 2018	82	75	1
Feb 2018	88	79	3
Mar 2018	156	150	6
Apr 2018	96	96	7
May 2018	133	128	14
Jun 2018	133	119	9
Jul 2018	111	109	10
Aug 2018	97	97	4
Sep 2018	103	103	10
Oct 2018	159	143	20
Nov 2018	156	150	14
Dec 2018	170	168	1
Jan 2019	178	172	2
Feb 2019	152	148	8
Mar 2019	107	106	6
Apr 2019	158	149	7
May 2019	137	132	6
Jun 2019	94	94	4
Jul 2019	62	57	5
Aug 2019	53	53	5
Sep 2019	68	62	5
Oct 2019	109	107	6
Nov 2019	115	108	13
Dec 2019	209	205	5
Jan 2020	127	121	16
Feb 2020	87	84	10
Mar 2020	90	86	7
Apr 2020	122	118	3
May 2020	49	45	8
Jun 2020	72	63	11
Jul 2020	89	61	6
Aug 2020	87	87	13
Sep 2020	133	127	8
Oct 2020	210	194	17
Nov 2020	174	165	19
Dec 2020	117	109	14
Jan 2021	144	136	8
Feb 2021	147	139	14
Mar 2021	162	146	16
Apr 2021	152	142	3
May 2021	124	122	13
Jun 2021	98	107	8
Jul 2021	100	108	6
Aug 2021	113	122	12
Sep 2021	134	140	9
Oct 2021	146	143	34
Nov 2021	108	117	20
Dec 2021	192	191	14
Jan 2022	142	137	5
Feb 2022	179	184	10
Mar 2022	199	208	9
Apr 2022	226	214	8
May 2022	230	205	19
Jun 2022	153	151	6
Jul 2022	221	216	11
Aug 2022	225	219	10
Sep 2022	225	223	11
Oct 2022	278	268	12
Nov 2022	230	228	11
Dec 2022	133	128	11
Jan 2023	173	165	8
Feb 2023	222	219	11
Mar 2023	330	318	10
Apr 2023	262	243	11
May 2023	381	373	21
Jun 2023	447	436	6
Jul 2023	605	601	12
Aug 2023	756	752	23
Sep 2023	1004	984	16
Oct 2023	875	874	7
Nov 2023	672	666	7
Dec 2023	631	80	2
Jan 2024	79	9	5
Feb 2024	81	8	2
Mar 2024	108	4	4
Apr 2024	153	23	3
May 2024	111	5	5
Jun 2024	135	2	1
Jul 2024	196	22	8
Aug 2024	180	1	1
Sep 2024	153	8	5
Total	27026	50716	3775

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