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Systemic biomarkers of inflammation, oxidative stress and tissue injury and repair among waterpipe, cigarette and dual tobacco smokers
  1. Naushad Ahmad Khan1,
  2. Gina Lawyer1,
  3. Samantha McDonough1,
  4. Qixin Wang1,
  5. Noura O Kassem2,
  6. Flora Kas-Petrus2,
  7. Dongxia Ye1,
  8. Kameshwar P Singh1,
  9. Nada O F Kassem2,
  10. Irfan Rahman1
  1. 1Department of Environmental Medicine, University of Rochester, Rochester, New York, USA
  2. 2Hookah Studies Division, Center for Behavioral Epidemiology and Community Health, San Diego State University, San Diego, California, USA
  1. Correspondence to Dr Irfan Rahman, Department of Environmental Medicine, University of Rochester, Rochester, NY 14642, USA; Irfan_Rahman{at}URMC.Rochester.edu

Footnotes

  • NAK and GL contributed equally.

  • Contributors NAK, NOFK, IR conceived and designed the experiments, wrote and edited the manuscript. KPS did data analysis, wrote and edited the manuscript. IR and NOFK obtained research funding and study design and experimental plans/assays. NAK, GL, NOK, FKP recruited the volunteers. NAK, GL, QW, DY, SRM, NOK, FKP performed the experiments. All authors contributed to manuscript preparation and approved the final version prior to submission.

  • Funding This work was supported in part by a National Institutes of Health (NIH) Grants, NIH 1R01HL135613, NIH 1R01HL085613 and the Food and Drug Administration (FDA) Center for Tobacco Products (CTP) via the National Institute on Drug Abuse (NIDA) of the NIH, NIHFDACTP grant# 1R01DA042470 (to Irfan Rahman) and R01DA042471 (to Nada O.F. Kassem). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH or the FDA.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Ethics approval Cohort I: approved by the General Clinical Research Center of the University of Rochester Research Subjects Review Board (IRB#RSRB00063526). Cohort II: Study procedures were approved by the San Diego State University Institutional Review Board (IRB# 2445100).

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article or uploaded as supplementary information.

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Footnotes

  • NAK and GL contributed equally.

  • Contributors NAK, NOFK, IR conceived and designed the experiments, wrote and edited the manuscript. KPS did data analysis, wrote and edited the manuscript. IR and NOFK obtained research funding and study design and experimental plans/assays. NAK, GL, NOK, FKP recruited the volunteers. NAK, GL, QW, DY, SRM, NOK, FKP performed the experiments. All authors contributed to manuscript preparation and approved the final version prior to submission.

  • Funding This work was supported in part by a National Institutes of Health (NIH) Grants, NIH 1R01HL135613, NIH 1R01HL085613 and the Food and Drug Administration (FDA) Center for Tobacco Products (CTP) via the National Institute on Drug Abuse (NIDA) of the NIH, NIHFDACTP grant# 1R01DA042470 (to Irfan Rahman) and R01DA042471 (to Nada O.F. Kassem). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH or the FDA.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Ethics approval Cohort I: approved by the General Clinical Research Center of the University of Rochester Research Subjects Review Board (IRB#RSRB00063526). Cohort II: Study procedures were approved by the San Diego State University Institutional Review Board (IRB# 2445100).

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement All data relevant to the study are included in the article or uploaded as supplementary information.

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