Introduction

The US Food and Drug Administration issued a final rule in 2016 deeming new tobacco products (any product made or derived from tobacco that is intended for human consumption, including any component, part or accessory of a tobacco product) under its authority. The products include electronic nicotine delivery systems, also referred to as vapes, vaporisers or electronic cigarettes, and products meeting the statutory definition that may be developed in the future.1 The US Agriculture Improvement Act of 20182 (known as the Farm Bill) removed hemp from the definition of marijuana in the Controlled Substance Act, effectively legalising cannabis-derived products with delta-9-tetrahydrocannabinol (THC) concentrations of no more than 0.3%. In contrast to high-THC cannabis products legally sold in some states, products primarily featuring cannabidiol (CBD) are now widely available in many forms nationally, including vaping liquids for use in vaping devices.3 4

Despite the availability of CBD products consumed with vaping devices, there is little research …