Footnotes

• Twitter @otg2014, @crisdelnevo

• Contributors CDD and AAS obtained funding and conceptualised the idea. CDD, EML and EMT analysed the data. OG wrote the first draft and all authors provided input on subsequent drafts. All authors have approved the final manuscript.

• Funding This research was funded by the National Cancer Institute (NCI) of the National Institutes of Health (NIH) and the US Food and Drug Administration (FDA) Center for Tobacco Products under U54CA229973. OG was additionally supported by funding from the Rutgers Cancer Institute of New Jersey (P30CA072720-5931). MJ was supported by funding from NCI (K01CA242591).

• Disclaimer The content is solely the responsibility of the authors and does not necessarily represent the official views of the NCI or FDA.

• Competing interests None declared.

• Provenance and peer review Not commissioned; externally peer reviewed.