RT Journal Article SR Electronic T1 The case of the disappearing nitrosamines: a potentially global phenomenon JF Tobacco Control JO Tob Control FD BMJ Publishing Group Ltd SP 13 OP 16 DO 10.1136/tc.2003.005579 VO 13 IS 1 A1 Gray, N A1 Boyle, P YR 2004 UL http://tobaccocontrol.bmj.com/content/13/1/13.abstract AB The cigarette usually carries in its smoke significant doses of carcinogenic tobacco specific nitrosamines (TSNAs), which have been implicated as causes of oral, lung, oesophageal, and pancreatic cancer. However, there is substantial variation in nitrosamine content of the smoke of modern cigarettes. This variation is both unacceptable and unnecessary, as TSNAs can be readily removed during the manufacturing process. Removing a known carcinogen needs no justification, even though proof of benefit may not be forthcoming for decades.