TY - JOUR T1 - Heated tobacco products likely appeal to adolescents and young adults JF - Tobacco Control JO - Tob Control SP - s41 LP - s47 DO - 10.1136/tobaccocontrol-2018-054596 VL - 27 IS - Suppl 1 AU - Karma McKelvey AU - Lucy Popova AU - Minji Kim AU - Benjamin W Chaffee AU - Maya Vijayaraghavan AU - Pamela Ling AU - Bonnie Halpern-Felsher Y1 - 2018/11/01 UR - http://tobaccocontrol.bmj.com/content/27/Suppl_1/s41.abstract N2 - Background Beginning in the 1960s in the USA and globally since 1998, tobacco companies have beenaggressively promoting heated tobacco products (HTP). In 2016, Philip Morris International (PMI) applied to the US Food and Drug Administration (FDA) seeking authorisation to market their IQOS HTP system and flavoured ‘HeatSticks’ in the USA as a modified-risk tobacco product (MRTP).Methods We systematically evaluated the publicly available data PMI submitted to FDA in its MRTP application to determine whether PMI’s IQOS product meets the US Tobacco Control Act’s standard for MRTP claims. We examined whether PMI provided sufficient data showing tobacco users will not initiate with IQOS, that youth will not misperceive the MRTP-related claims being made concerning IQOS, and how youth perceive health risks associated with IQOS.Results PMI’s own studies failed to provide evidence that youth, including non-users and former users, will not find IQOS appealing, will not initiate use of IQOS and will not perceive these products as risk-free. Further, PMI did not refer to independent studies conducted among adolescents which could influence their conclusions. Finally, their studies suffered from design and implementation flaws and cannot be relied on to support the proffered claims.Conclusion PMI’s own data and available evidence from scientific studies conducted independent of the tobacco industry regarding how novel tobacco products are currently being marketed suggest that introduction of IQOS will result in adolescent and young adult non-users initiating tobacco use with IQOS and could also increase poly-use of IQOS along with other tobacco products. ER -