RT Journal Article SR Electronic T1 Impact of e-cigarette retail displays on attitudes to smoking and vaping in children: an online experimental study JF Tobacco Control JO Tob Control FD BMJ Publishing Group Ltd SP tobaccocontrol-2021-056980 DO 10.1136/tobaccocontrol-2021-056980 A1 Anna K M Blackwell A1 Mark A Pilling A1 Katie De-Loyde A1 Richard W Morris A1 Laura A Brocklebank A1 Theresa M Marteau A1 Marcus R Munafò YR 2022 UL http://tobaccocontrol.bmj.com/content/early/2022/04/13/tobaccocontrol-2021-056980.abstract AB Objectives To estimate the impact of electronic cigarette (e-cigarette) retail display exposure on attitudes to smoking and vaping (susceptibility to tobacco smoking and using e-cigarettes, and perceptions of the harms of smoking and e-cigarette use).Design Between-subjects randomised experiment using a 2 (e-cigarette retail display visibility: high vs low)×2 (proportion of e-cigarette images: 75% vs 25%) factorial design.Setting Online via the Qualtrics survey platform.Participants UK children aged 13–17 years (n=1034), recruited through a research agency.Intervention Participants viewed 12 images of retail displays that contained e-cigarette display images or unrelated product images. E-cigarette display images were either high or low visibility, based on a conspicuousness score. Participants were randomised to one of four groups, with e-cigarette display visibility and proportion of e-cigarette images, compared with images of unrelated products, manipulated: (1) 75% e-cigarettes, high visibility; (2) 25% e-cigarettes, high visibility; (3) 75% e-cigarettes, low visibility; (4) 25% e-cigarettes, low visibility.Main outcome measures The primary outcome was susceptibility to smoking (among never smokers only). Secondary outcomes were susceptibility to using e-cigarettes (among never vapers only), and perceptions of smoking and e-cigarette harm (all participants).Results Neither e-cigarette retail display visibility, nor the proportion of e-cigarette images displayed, appeared to influence susceptibility to smoking (visibility: OR=0.84, 95% CI 0.62 to 1.13, p=0.24; proportion: OR=1.34, 95% CI 1.00 to 1.82, p=0.054 (reference: low visibility, not susceptible)).Planned subgroup analyses indicated that exposure to a higher proportion of e-cigarette images increased susceptibility to smoking among children who visited retail stores more regularly (n=524, OR=1.59, 95% CI 1.04 to 2.43, p=0.034), and those who passed the attention check (n=880, OR=1.43, 95% CI 1.03 to 1.98, p=0.031).In addition, neither e-cigarette retail display visibility nor the proportion of e-cigarette images displayed, appeared to influence susceptibility to using e-cigarettes (visibility: OR=1.07, 95% CI 0.80 to 1.43, p=0.65; proportion: OR=1.22, 95% CI 0.91 to 1.64, p=0.18).Greater visibility of e-cigarette retail displays reduced perceived harm of smoking (mean difference (MD)=−0.19, 95% CI −0.34 to −0.04, p=0.016). There was no evidence that the proportion of e-cigarette images displayed had an effect (MD=−0.07, 95% CI −0.22 to 0.09, p=0.40).Perceived harm of e-cigarette use did not appear to be affected by e-cigarette retail display visibility (MD=−0.12, 95% CI −0.28 to 0.05, p=0.16) or by the proportion of e-cigarette images displayed (MD=−0.10, 95% CI −0.26 to 0.07, p=0.24).Conclusions There is no evidence in the full sample to suggest that children’s susceptibility to smoking is increased by exposure to higher visibility e-cigarette retail displays, or to a higher proportion of e-cigarette images. However, for regular store visitors or those paying more attention, viewing a higher proportion of e-cigarette images increased susceptibility to smoking. In addition, viewing higher visibility e-cigarette images reduced perceived harm of smoking. A review of the current regulatory discrepancy between tobacco and e-cigarette point-of-sale marketing is warranted.Trial registration number ISRCTN18215632.Data are available in a public, open access repository. The datasets generated and analysed during the current study are available at the University of Bristol data repository, data.bris, at: 10.5523/bris.glkgioxkg9ue2gidk6gktm7pd