RT Journal Article SR Electronic T1 Role of affective reactivity induced by cigarette packaging including graphic warning labels: the CASA Study JF Tobacco Control JO Tob Control FD BMJ Publishing Group Ltd SP 315 OP 322 DO 10.1136/tobaccocontrol-2021-056650 VO 32 IS 3 A1 Matthew Stone A1 David Strong A1 Claudiu Dimofte A1 Elizabeth Brighton A1 Jesica Oratowski A1 Tingyi Yang A1 Manar Alkuzweny A1 Atean Asslani A1 Katherine Velasco A1 Michael Skipworth A1 Noe C Crespo A1 Samantha Hurst A1 Eric C Leas A1 Kim Pulvers A1 John P Pierce YR 2023 UL http://tobaccocontrol.bmj.com/content/32/3/315.abstract AB Objective To identify whether three types of cigarette pack designs, including three versions of graphic warning label (GWL) plain packs, one GWL absent and branding absent pack (blank) and the smoker’s own GWL absent and branding present pack (US), elicit different valence, type and levels of affect.Design US daily smokers (n=324) were asked to handle each of the five pack types and ‘think aloud’ their reactions. To avoid a muted familiarity response, exposure to their own US pack followed exposure to at least one GWL plain pack. Reactions were scored on a reactivity scale (−3 to +3) and the text was coded for speech polarity (−1 to +1) and emotive word frequency.Results Reactivity scores had excellent inter-rater reliability (agreement ≥86%; intraclass correlation coefficient ≥0.89) and were correlated with speech polarity (r=0.21–0.37, p<0.001). When considering their US pack, approximately two-thirds of smokers had a low (31.5%) to medium (34.6%) positive response (reactivity=1.29; polarity=0.14) with expressed feelings of joy and trust. Blank packaging prompted a largely (65.4%) neutral response (reactivity=0.03; polarity=0.00). The gangrenous foot GWL provoked mostly medium (46.9%) to high (48.1%) negative responses (reactivity=−2.44; polarity=−0.20), followed by neonatal baby (reactivity=−1.85; polarity=−0.10) and throat cancer (reactivity=−1.76; polarity=−0.08) warnings. GWLs varied in their elicitation of disgust, anger, fear and sadness.Conclusion Initial reactions to GWL packs, a blank pack, and smokers’ current US pack reflected negative, neutral, and positive affect, respectively. Different versions of the GWL pack elicited different levels and types of immediate negative affect.Data are available upon reasonable request. Deidentified data and a measures codebook will be made available on request.