PT - JOURNAL ARTICLE AU - Mann, Nathan AU - Spencer, Garrison AU - Hutchinson, Brian AU - Ngongo, Carrie AU - Tarlton, Dudley AU - Webb, Douglas AU - Grafton, Daniel AU - Nugent, Rachel TI - Interpreting results, impacts and implications from WHO FCTC tobacco control investment cases in 21 low-income and middle-income countries AID - 10.1136/tc-2023-058337 DP - 2024 May 01 TA - Tobacco Control PG - s17--s26 VI - 33 IP - Suppl 1 4099 - http://tobaccocontrol.bmj.com/content/33/Suppl_1/s17.short 4100 - http://tobaccocontrol.bmj.com/content/33/Suppl_1/s17.full SO - Tob Control2024 May 01; 33 AB - Background Tobacco control investment cases analyse the health and socioeconomic costs of tobacco use and the benefits that can be achieved from implementing measures outlined in the WHO Framework Convention on Tobacco Control (WHO FCTC). They are intended to provide policy-makers and other stakeholders with country-level evidence that is relevant, useful and responsive to national priorities and policy context.Methods This paper synthesises findings from investment cases conducted in Armenia, Cabo Verde, Cambodia, Chad, Colombia, Costa Rica, El Salvador, Eswatini, Georgia, Ghana, Jordan, Laos, Madagascar, Myanmar, Nepal, Samoa, Sierra Leone, Sri Lanka, Suriname, Tunisia and Zambia. We examine annual socioeconomic costs associated with tobacco use, focusing on smoking-related healthcare expenditures, the value of lives lost due to tobacco-related mortality and workplace productivity losses due to smoking. We explore potential benefits associated with WHO FCTC tobacco demand-reduction measures.Results Tobacco use results in average annual socioeconomic losses of US$95 million, US$610 million and US$1.6 billion among the low-income (n=3), lower-middle-income (n=12) and upper-middle-income countries (n=6) included in this analysis, respectively. These losses are equal to 1.1%, 1.8% and 2.9% of average annual national gross domestic product, respectively. Implementation and enforcement of WHO FCTC tobacco demand-reduction measures would lead to reduced tobacco use, fewer tobacco-related deaths and reduced socioeconomic losses.Conclusions WHO FCTC tobacco control measures would provide a positive return on investment in every country analysed.Data sharing not applicable as no datasets generated and/or analysed for this study.