Table 1

Potential reduced exposure products (PREPs)

Category Descriptors Examples
Modified tobaccoReduced yield of selected toxicantsAdvance™, low nitrosamine tobacco cigarettes, Snus, reduced nitrosamine smokeless tobacco
Cigarette-like productsLess combustion than cigarettesPremier™ (off market)
Pharmaceutic al productsNicotine replacement Nicotine gum, patches, inhaler, nasal spray
Antidepressants that reduce nicotine cravingBupropion SR, nortriptyline
Other medicationsNicotine antagonists, clonidine