Summary table of cancer risk indices for individual chemical constituents of cigarette smoke based on exposure to a single cigarette per day
| Toxicant category* | Mainstream smoke constituent | CRI per cigarette/day |
|---|---|---|
| *1, aldehydes and small organics from combustion; 2, metals; 3, nitrosamines; 4, miscellaneous compounds; and 5, polycyclic aromatics (PAHs). | ||
| †No cancer unit risk value was available for NNK. The unit risk from NNN was used as a surrogate for this tobacco specific nitrosamine. | ||
| 1 | 1,3–Butadiene | 3.02E–04 |
| 1 | Acrylonitrile | 1.29E–04 |
| 2 | Arsenic | 1.16E–04 |
| 1 | Acetaldehyde | 9.18E–05 |
| 1 | Benzene | 6.71E–05 |
| 1 | Acetamide | 4.70E–05 |
| 3 | N-Nitrosonornicotine (NNN) | 3.80E–05 |
| 3 | N-Nitrosopyrrolidine (NP) | 3.39E–05 |
| 2 | Chromium (hexavalent) | 3.15E–05 |
| 2 | Cadmium | 2.16E–05 |
| 1 | Formaldehyde | 9.90E–06 |
| 4 | Hydrazine | 8.33E–06 |
| 3 | 4-N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) | 7.80E–06† |
| 3 | N-Nitrosodimethylamine (NDMA) | 5.58E–06 |
| 4 | DDT | 4.61E–06 |
| 3 | N-Nitrosodiethylamine (NDEA) | 4.27E–06 |
| 5 | Benzo(a)pyrene | 1.93E–06 |
| 3 | N-Nitroso-N-dibutylamine | 1.89E–06 |
| 3 | N-Nitrosoethyl-methylamine | 1.89E–06 |
| 5 | Dibenzo(a,i)pyrene | 1.38E–06 |
| 3 | N-Nitrosodiethanolamine | 1.20E–06 |
| 3 | N Nitrosopiperidine | 6.04E–07 |
| 1 | Urethane | 4.14E–07 |
| 4 | 4-Aminobiphenyl | 3.60E–07 |
| 5 | Benzo(j)fluoranthene | 3.30E–07 |
| 5 | Benz(a)anthracene | 2.48E–07 |
| 5 | Dibenz(a,h)anthracene | 2.40E–07 |
| 5 | 2-Aminonaphthalene | 1.80E–07 |
| 5 | Benzo(b)fluoranthene | 1.65E–07 |
| 2 | Nickel | 1.43E–07 |
| 5 | Indeno(1,2,3-c,d)pyrene | 6.60E–08 |
| 3 | N-Nitroso-N-propylamine | 5.00E–08 |
| 5 | Benz(k)fluoranthene | 4.95E–08 |
| 5 | 7H-Dibenzo(c,g)-carbazole | 3.85E–08 |
| 1 | Vinyl chloride | 3.35E–08 |
| 5 | 5-Methylchrysene | 3.30E–08 |
| 2 | Beryllium | 3.00E–08 |
| 5 | Chrysene | 2.75E–08 |
| 5 | Dibenz(a,j)acridine | 1.49E–08 |
| 2 | Lead | 7.68E–09 |
| 5 | Dibenz(a,h)acridine | 5.50E–10 |