Table 1

 Model uncertainty assumptions

ParameterUncertaintyType of distributionSource
NRT, nicotine replacement therapy.
OR of quitting—NRT1.73 (1.62 to 1.85)TriangularSilagy, et al10
OR of quitting—bupropion2.54 (1.9 to 3.41)TriangularWoolacott, et al2
Background quit rate8.6% (7.9% to 9.3%)TriangularSilagy, et al10
Intervention costs—NRTA$490 (A$220–890)TriangularOwn survey; variation in treatment length and strength
Intervention costs—patient contribution to bupropionA$36–96UniformVariation in patient contributions
Relapse after initial cessation10–48%UniformMikkelsen et al, Blondal et al, Daughton et al and Yudkin et al22–25