Table 2

 Variables used in the analysis

VariableBase case (range for sensitivity analysis)
*Odds ratio for smoking cessation at one year, as compared to no intervention.
†Incremental odds ratio for cessation at one year, as compared to counselling only (identical OR for women and men).
Natural cessation rate among all smokers, %2.5 (1–4)
Proportion of smokers in “preparation” stage, %25 (10–40)
OR* counselling only1.73 (1.46–2.03)
OR† nicotine gum1.66 (1.52–1.82)
OR† nicotine patch1.80 (1.61–2.01)
OR† nicotine spray2.35 (1.63–3.38)
OR† nicotine inhaler2.14 (1.44–3.18)
OR† bupropion2.51 (1.5–3.0)
Smokers still under treatment after first month (%)50 (40–60)
Smokers still under treatment after second month (%)20 (15–25)
Lifetime probability of relapse after one year of abstinence (%)35 (10–50)
Time required for counselling (minutes)10
Additional physician time required (minutes)90
Cost per hour of physicians’ time, US$
    Canada67
    France83
    Spain33
    Switzerland65
    United Kingdom134
    United States108
Discount rate, %3 (0–5)