Table 1

Statistical analyses results for all measures

Condition (C)Use (U)Time (T)C×UC×TU×TC×U×T
FpFpFpFpFpFpFp
Physiological effects
 Plasma nicotine*48.5<0.00144.6<0.00156.6<0.00110.3<0.00147.6<0.0013.5<0.051.7NS
 Heart rate*7.0<0.00135.8<0.00162.9<0.0012.3<0.0524.3<0.00118.0<0.0012.9<0.001
 Expired air CO59.7<0.00138.8<0.001116.4<0.001147.8<0.001156.4<0.0012.1NS1.9NS
Subjective effects QSU brief*
 Factor 111.4<0.00111.8<0.0131.3<0.0013.1<0.0510.7<0.0012.1NS1.0NS
 Factor 24.9<0.011.1NS8.7<0.012.2NS4.4<0.0012.0NS1.4NS
Hughes–Hatsukami*
 Urges to smoke10.4<0.0016.1<0.0537.2<0.0011.2NS6.7<0.0014.3<0.051.0NS
 Irritability/frustration/anger2.6<0.051.9NS7.2<0.0011.9NS1.6NS3.2<0.051.5NS
 Anxious2.5<0.050.1NS7.4<0.0010.5NS0.8NS6.8<0.010.7NS
 Difficulty concentrating1.6NS0.0NS3.7<0.051.5NS0.9NS1.4NS1.3NS
 Restlessness1.4NS1.2NS6.6<0.012.2NS1.1NS3.9<0.050.9NS
 Hunger1.3NS7.9<0.015.8<0.011.8NS1.5NS0.8NS1.2NS
 Impatient3.2<0.050.2NS6.2<0.011.4NS1.5NS4.1<0.011.2NS
 Craving a cigarette/nicotine11.3<0.0019.6<0.0129.2<0.0012.9<0.056.9<0.0015.8<0.011.4NS
 Drowsiness0.4NS0.1NS4.9<0.011.5NS1.0NS3.6<0.051.5NS
 Depression/feeling blue0.8NS0.4NS0.8NS1.1NS1.1NS0.6NS1.2NS
 Desire for sweets1.8NS0.5NS2.7NS2.0NS1.3NS2.8<0.050.8NS
Direct effects of nicotine*
 Nauseous2.9<0.050.0NS4.7<0.051.8NS2.5<0.051.9NS1.4NS
 Dizzy2.1NS0.1NS4.4<0.011.1NS1.6NS1.5NS2.3<0.05
 Lightheaded1.7NS0.1NS5.0<0.011.0NS2.3<0.050.5NS1.2NS
 Nervous0.7NS0.4NS1.1NS1.9NS1.5NS1.3NS1.1NS
 Sweaty0.7NS1.9NS1.7NS1.1NS2.0NS1.1NS1.0NS
 Headache1.6NS4.1NS2.2NS1.3NS2.1<0.051.9NS1.0NS
 Excessive salivation5.9<0.0010.8NS17.0<0.0011.5NS4.8<0.0012.8<0.051.6NS
 Heart pounding3.2<0.050.9NS1.2NS0.5NS0.9NS1.1NS1.2NS
 Confused2.4NS2.0NS0.7NS1.0NS0.9NS1.1NS0.6NS
 Weak1.3NS2.9NS0.9NS0.7NS1.0NS1.0NS0.8NS
Direct effects of tobacco*
 Satisfy35.9<0.00131.1<0.00154.5<0.0014.4<0.0115.5<0.00130.7<0.0017.7<0.001
 Pleasant30.9<0.00116.6<0.00159.2<0.0013.7<0.0113.5<0.00134.4<0.0018.7<0.001
 Taste good24.9<0.00116.4<0.00150.6<0.0016.6<0.0019.5<0.00138.4<0.0016.6<0.001
 Dizzy6.3<0.0010.5NS8.2<0.0012.5<0.051.8NS11.0<0.0013.6<0.01
 Calm11.3<0.0011.3NS26.0<0.0012.5<0.055.1<0.00127.7<0.0013.7<0.001
 Help concentrate9.5<0.0015.6<0.0513.8<0.0011.3NS3.2<0.0110.4<0.0012.4<0.01
 Feel awake11.5<0.0011.8NS21.3<0.0010.6NS3.4<0.00117.5<0.0013.2<0.01
 Reduce hunger3.3<0.019.0<0.0114.6<0.0010.2NS1.7NS17.9<0.0012.1<0.05
 Feel sick5.2<0.011.3NS11.4<0.0010.6NS2.7<0.056.8<0.011.8NS
 Taste like own brand55.8<0.00124.1<0.00132.1<0.00112.8<0.00122.9<0.00119.5<0.00116.3<0.001
 Feel like own brand48.4<0.00122.3<0.00136.9<0.0018.3<0.00122.2<0.00123.3<0.00113.7<0.001
 Harsh as own brand13.9<0.00111.9<0.0122.9<0.0014.1<0.015.3<0.00117.5<0.0014.0<0.001
 Mild as own brand34.6<0.0018.8<0.0133.6<0.0014.7<0.0111.1<0.00121.7<0.0019.8<0.001
 More of product right now17.4<0.0010.7NS12.6<0.0010.8NS3.4<0.00140.1<0.00110.9<0.001
  • * dfC=(6162); dfU=(1,27); dfT=(4108); dfC×U=(6162); dfC×T=(24 648); dfU×T=(4108); dfC×U×T=(24 648).

  • dfC=(6162); dfU=(1,27); dfT=(2,54); dfC×U=(6162); dfC×T=(12 324); dfU×T=(2,54); dfC×U×T=(12 324).