Table 4

Adverse events reported by participants after 9 h of product use, by product

Adverse event	ENDD 0 mg		ENDD 16 mg		Nicorette inhalator
Adverse event	n/N^*	(%)	n/N	(%)	n/N	(%)
Mouth/throat irritation^†	14/64	22	22/58	38	36/41	88
Aching jaws	4/35	11	3/37	8	2/37	5
Nausea	6/33	18	9/31	29	6/33	18
Flatulence/belching/hiccups/heartburn	6/111	5	6/113	5	11/147	23
Vertigo/feeling high	9/69	9	14/66	21	12/66	18
Headache	7/32	22	6/34	18	6/33	18
Sweatiness/clammy skin	3/75	4	3/77	4	2/76	3
Palpitations	0/38	0	2/38	5	0/39	0

ENDD, electronic nicotine delivery device.
↵* n=number of events, N=numbers of participants in each group. In some cases, groups were pooled because of similarity of symptoms, hence the large numbers.
↵† ENDD 0 mg versus inhalator p<0.001; ENDD 16 mg versus inhalator p<0.001.