Eligibility criteria in 54 randomised clinical trials assessing pharmacotherapies for smoking cessation
| Eligibility criteria present in more than 10% of the studies (ranked by frequency) | Studies using the criteria (reference number) | Number of studies using the criteria (n=54) |
| 1. Pregnancy | 37 38 43–48 50–54 56 58–65 67–69 71–82 84 93 94 | 40 |
| 2. Cardiovascular disorder | 37 38 41–46 48 49 51–53 58–62 64 65 67–69 71–76 78–82 84 85 92–94 | 38 |
| 3. Smoking at least 10 cigarettes per day on average | 37–49 53–56 58–63 66 67 69–74 76 78 79 83 89 92 | 37 |
| 4. Currently/past 6 months take any psychotropic medication | 38 39 42 45 47 49 52–54 56 58–60 62–64 66–72 74–76 78 79 81 82 89 | 32 |
| 5. Alcohol dependence | 38 40–44 47 48 50 53 54 58–60 62–65 68 70–72 74–76 78 79 81 82 86 | 30 |
| 6. Motivated to quit | 37–39 43 44 46 48–51 54 55 58 59 61 63 65 67 69 71–73 76 78 79 81 82 87 93 | 29 |
| 7. Dependence on other drugs | 38 40–44 50 54 58–60 62–66 68 70–72 74–76 78 79 81 82 | 27 |
| 8. Having current depression | 37 38 40–43 45–49 52 54 55 59 63 66 70 73 74 76 77 | 22 |
| 9. Currently/past 6 months take bupropion and/or NRT | 39–43 46 51–55 58 59 61 63 64 66 69 78 81 87 | 21 |
| 10. Eating disorder | 37–39 41–44 47–49 52 54 55 59 63 66 70 73 74 76 | 20 |
| 11. Having a current psychosis | 37 38 40–43 47–49 52 59 63 66 70 73 74 76 77 86 | 19 |
| 12. Bipolar disorder | 37 38 40–43 47–49 52 59 63 66 70 73 74 76 77 | 18 |
| 13. Having current panic disorder | 37 38 40–43 47–49 59 63 66 70 73 74 76 77 | 17 |
| 14. Using any form of tobacco other than cigarettes | 38 40 42 46 48 53 59–61 64 71 74 75 79 82 87 | 16 |
| 15. Age less than 75 years | 38 40–45 60 62 69 74–77 81 94 | 16 |
| 16. Renal disease | 37–39 41–46 48 49 55 59 92 | 14 |
| 17. History/risk of seizure | 39 41 43 44 46–49 52 54 55 59 63 | 13 |
| 18. High blood pressure | 41–45 48 49 51 59 68 69 72 81 | 13 |
| 19. Liver disease | 37–39 41–46 48 49 55 92 | 13 |
| 20. Skin disorder | 58 60 62 67 69 71 73 74 76 77 79 80 82 | 13 |
| 21. Neurological disease | 37–39 41 44 48 49 55 59 92 | 10 |
| 22. Peptic ulcer disease | 45 51 59 68 71 72 80 84 94 | 9 |
| 23. Diabetes | 9 13 22–24 35 38 51 53 | 9 |
| 24. High alveolar carbon monoxide level | 53 55 56 70 74 76 | 6 |
| 25. Allergies | 43 48 52 65 69 70 | 6 |
| Studies that did not report any inclusion/exclusion criteria | 55–59 | 5 |