Categories | n* | Cases* | HR† | 95% CI | RAP† | 95% CI | |
---|---|---|---|---|---|---|---|
Smoking status | Never smoker | 3412 | 346 | ref | Ref | ||
Former smoker | 2104 | 357 | 1.33 | 1.13 to 1.57 | 3.3 | 1.3 to 5.3 | |
Current smoker | 802 | 204 | 2.53 | 2.10 to 3.03 | 10.7 | 8.0 to 13.4 | |
Number of currently smoked cigarettes | Never smoker | 3412 | 346 | ref | Ref | ||
1–10 | 316 | 63 | 1.86 | 1.40 to 2.45 | 6.5 | 3.3 to 9.7 | |
11–20 | 340 | 91 | 2.83 | 2.23 to 3.60 | 11.0 | 7.7 to 14.2 | |
>20 | 147 | 50 | 3.91 | 2.87 to 5.34 | 14.4 | 10.2 to 18.5 | |
per 10 increase | 1.51 | 1.41 to 1.62 | 4.5 | 3.5 to 5.5 | |||
Pack-years of smoking | 0 | 3435 | 350 | ref | ref | ||
<20 | 1016 | 143 | 1.33 | 1.08 to 1.63 | 3.3 | 0.8 to 5.8 | |
20–<40 | 902 | 194 | 1.98 | 1.63 to 2.39 | 7.9 | 5.3 to 10.6 | |
≥40 | 527 | 157 | 2.50 | 2.03 to 3.09 | 10.7 | 7.5 to 13.9 | |
per 10 increase | 1.18 | 1.14 to 1.22 | 1.9 | 1.4 to 2.5 | |||
Years since smoking cessation | Never smoker | 3412 | 346 | ref | ref | ||
<10 | 658 | 133 | 1.74 | 1.42 to 2.14 | 6.2 | 3.7 to 8.7 | |
10–19 | 548 | 102 | 1.50 | 1.19 to 1.89 | 4.6 | 1.9 to 7.3 | |
≥20 | 1124 | 159 | 1.02 | 0.83 to 1.25 | 0.2 | −2.1 to 2.5 | |
Current smoker | 803 | 204 | ref | ref | |||
<10 | 658 | 133 | 0.70 | 0.56 to 0.88 | −4.0 | −6.5 to (−1.4) | |
10–19 | 548 | 102 | 0.61 | 0.48 to 0.77 | −5.6 | −8.4 to (−2.8) | |
≥20 | 1124 | 159 | 0.41 | 0.33 to 0.51 | −10.0 | −12.7 to (−7.2) |
Bold printed: statistically significant findings (p<0.05).
*Numbers for unimputed dataset.
†adjusted for age, sex, education (≤9 years, 10–11 years, ≥12 years), alcohol consumption (abstainer, low intake, medium intake, high intake which were defined as follows: men: 0.1–39.9 g/week, 40–59.9 g/week, ≥60 g/week, women: 0.1–19.9 g/week, 20–39.9 g/week, ≥40 g/week, respectively), body mass index (<18.5 kg/m2, 18.5–25.0 kg/m2, 25.1–29.9 kg/m2, ≥30 kg/m2), diabetes, systolic blood pressure, total cholesterol, history of stroke, history of myocardial infarction and history of cancer.
RAP, Rate advancement period.