Table 1

Associations of smoking and all-cause mortality

Categoriesn*Cases*HR†95% CIRAP†95% CI
Smoking status Never smoker3412346refRef
Former smoker2104357 1.33 1.13 to 1.57 3.3 1.3 to 5.3
Current smoker802204 2.53 2.10 to 3.03 10.7 8.0 to 13.4
Number of currently smoked cigarettes Never smoker3412346refRef
1–1031663 1.86 1.40 to 2.45 6.5 3.3 to 9.7
11–2034091 2.83 2.23 to 3.60 11.0 7.7 to 14.2
>2014750 3.91 2.87 to 5.34 14.4 10.2 to 18.5
per 10 increase 1.51 1.41 to 1.62 4.5 3.5 to 5.5
Pack-years of smoking 03435350refref
<201016143 1.33 1.08 to 1.63 3.3 0.8 to 5.8
20–<40902194 1.98 1.63 to 2.39 7.9 5.3 to 10.6
≥40527157 2.50 2.03 to 3.09 10.7 7.5 to 13.9
per 10 increase 1.18 1.14 to 1.22 1.9 1.4 to 2.5
Years since smoking cessation Never smoker3412346refref
<10658133 1.74 1.42 to 2.14 6.2 3.7 to 8.7
10–19548102 1.50 1.19 to 1.89 4.6 1.9 to 7.3
≥2011241591.020.83 to 1.250.2−2.1 to 2.5
Current smoker803204refref
<10658133 0.70 0.56 to 0.88 −4.0 −6.5 to (−1.4)
10–19548102 0.61 0.48 to 0.77 −5.6 −8.4 to (−2.8)
≥201124159 0.41 0.33 to 0.51 −10.0 −12.7 to (−7.2)
  • Bold printed: statistically significant findings (p<0.05).

  • *Numbers for unimputed dataset.

  • †adjusted for age, sex, education (≤9 years, 10–11 years, ≥12 years), alcohol consumption (abstainer, low intake, medium intake, high intake which were defined as follows: men: 0.1–39.9 g/week, 40–59.9 g/week, ≥60 g/week, women: 0.1–19.9 g/week, 20–39.9 g/week, ≥40 g/week, respectively), body mass index (<18.5 kg/m2, 18.5–25.0 kg/m2, 25.1–29.9 kg/m2, ≥30 kg/m2), diabetes, systolic blood pressure, total cholesterol, history of stroke, history of myocardial infarction and history of cancer.

  • RAP, Rate advancement period.