Plasma cotinine, urine cotinine plus 3-hydroxycotinine (COT + 3HC) and urine total 4-(methylnitrosoamino)-(3-pyridyl)1-butanol (NNAL) at baseline (BL), maximum concentration (Cmax) and maximum change (Δmax) following 1 h exposure to secondhand smoke in a vehicle
Plasma cotinine (ng/ml) | Urine cotinine (ng/ml) | Urine COT+3HC (nmol/mg creat) | Urine total NNAL (pg/mg creat) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Subject | BL | Cmax | Δmax | BL | Cmax | Δmax | BL | Cmax | Δmax | BL | Cmax | Δmax |
1 | 0 | 0.17 | 0.17 | 0.09 | 1.11 | 1.02 | 0.002 | 0.016 | 0.014 | 0 | 1.27 | 1.27 |
2 | 0.07 | 0.20 | 0.13 | 0.19 | 2.52 | 2.32 | 0.003 | 0.015 | 0.012 | 0 | 2.62 | 2.62 |
3 | 0.06 | 0.21 | 0.15 | 0.88 | 3.69 | 2.80 | 0.016 | 0.039 | 0.023 | 0 | 4.05 | 4.05 |
4 | 0.05 | 0.13 | 0.08 | 0.21 | 1.04 | 0.83 | 0.004 | 0.014 | 0.010 | 0 | 1.20 | 1.20 |
5 | 0.06 | 0.12 | 0.06 | 0.21 | 0.90 | 0.63 | 0.002 | 0.010 | 0.008 | 0 | 4.92 | 4.92 |
6 | 0 | 0.28 | 0.28 | 0.41 | 2.92 | 2.51 | 0.007 | 0.032 | 0.024 | 0.48 | 3.51 | 3.03 |
7 | 0.06 | 0.16 | 0.10 | 0.52 | 6.00 | 5.48 | 0.008 | 0.068 | 0.060 | 0 | 2.23 | 2.23 |
8 | 0.04 | 0.12 | 0.07 | 0.48 | 1.10 | 0.61 | 0.006 | 0.010 | 0.004 | 0.32 | 1.65 | 1.33 |
Average | 0.04 | 0.17 | 0.13 | 0.38 | 2.41 | 2.03 | 0.006 | 0.025 | 0.019 | 0.10 | 2.68 | 2.58 |
SD | 0.03 | 0.06 | 0.07 | 0.25 | 1.79 | 1.66 | 0.005 | 0.020 | 0.018 | 0.19 | 1.36 | 1.37 |
creat, creatinine.