Table 4

Adjusted analysis of air quality measures by number of active waterpipes, August–September 2012, Toronto Waterpipe Study

Air quality measuresModelWaterpipe levelAdjusted coefficient (95% CI)Exponential coefficient*p Value
PM2.5 (µg/m3)1†BackgroundReferent
0 active waterpipe0.19 (−0.18 to 0.55)1.210.552
1–4 active waterpipes0.67 (0.36 to 0.97)1.95<0.001
5–9 active waterpipes0.90 (0.68 to 1.12)2.46<0.001
10+ active waterpipes1.25 (1.01 to 1.49)3.49<0.001
2‡Linear trend0.30 (0.10 to 0.49)1.350.003
Ambient CO (ppm)1†BackgroundReferent
0 active waterpipe0.15 (−0.07 to 0.37)1.160.192
1–4 active waterpipes0.62 (0.44 to 0.80)1.86<0.001
5–9 active waterpipes1.21 (1.06 to 1.35)3.35<0.001
10+ active waterpipes1.28 (1.12 to 1.45)3.60<0.001
2‡Linear trend0.09 (−0.01 to 0.18)1.090.066
Nicotine (µg/m3)1†1–4 active waterpipesReferent
5–9 active waterpipes5.35 (−3.35 to 14.06)0.175
10+ active waterpipes4.73 (−0.24 to 9.70)0.058
2‡Linear trend1.97 (−0.32 to 4.27)0.070
  • *Real-time measures of PM2.5 and ambient CO were log transformed in adjusted analysis and exponentiated to normal scale.

  • †In model 1, the number of active waterpipes was treated as a categorical variable. Mixed-model analysis was used for real-time measures of PM2.5 and ambient CO, compared with background measures and adjusted for temperature, relative humidity and CO2. Ordinary linear regression was used for measures of nicotine, compared with the level with 1–4 active waterpipe and adjusted for temperature, relative humidity, CO2, venue volume and distance from the nearest active waterpipe to the monitor.

  • ‡In model 2, the number of active waterpipes was treated as a continuous variable (ie, 1, 2, 3 and 4 for levels with 0, 1–4, 5–9 and 10+ active waterpipes for PM2.5 and ambient CO in mixed model analysis; and 1, 2 and 3 for levels with 1–4, 5–9 and 10+ active waterpipes for nicotine measures in ordinary linear regression analysis). Analysis in model 2 was adjusted for temperature, relative humidity, CO2, venue volumes, door or window openings and distance from the nearest active waterpipe to monitors.

  • CO, carbon monoxide.