Table 1

Concentrations of flavour chemicals measured at ≥0.5 mg/mL and/or for top three flavour chemicals in 30 e-cigarette products including e-cigarettes with disposable cartridges (NJOY and BLU) and refill bottles (six brands)

Rank by total flavour levelFlavour name
(number for flavour)
Brand
Refill bottle or disposable cartridgeLabelled nicotine (mg/mL)Total for flavour chemicals determined (mg/mL)(mg/mL)Individual flavour chemicalsCAS Registry numberClass
1‘Double Dark Chocolate’
(1 of 2 Chocolate/Cocoa)
Zeus E-Juice
Refill bottle1243.033.0Vanillin121-33-5Aldehyde
4.7Maltol118-71-8Alcohol
3.5Ethyl maltol4940-11-8Alcohol
1.3Ethyl vanillin121-32-4Aldehyde
2‘Cotton Candy’
(1 of 2 Cotton Candy)
Mt Baker Vapor
Refill bottle1231.427.1Ethyl maltol4940-11-8Alcohol
3.8Ethyl vanillin121-32-4Aldehyde
0.5Vanillin121-33-5Aldehyde
3‘Wild Cherry’
(1 of 3 Cherry)
Mt Baker Vapor
Refill bottle1229.721.2Benzaldehyde100-52-7Aldehyde
2.8p-Tolualdehyde14-87-0Aldehyde
1.1Benzyl alcohol100-51-6Alcohol
0.7Limonene138-86-3*Monoterpene
0.5Ethyl butyrate105-54-4Ester
0.5Benzyl acetate140-11-4Ester
0.5γ-Undecalactone104-67-6Ketone
4‘555 Menthol’
(1 of 4 Menthol)
Mt Baker Vapor
Refill bottle1228.521.6Menthol2216-51-5*Alcohol
5.2Vanillin121-33-5Aldehyde
1.2Maltol118-71-8Alcohol
5‘Caught'n Pick'n Kid’
(2 of 2 Cotton Candy)
Rose City Vapors
Refill bottle1227.823.4Ethyl maltol4940-11-8Alcohol
4.0Ethyl vanillin121-32-4Aldehyde
0.4Vanillin121-33-5Aldehyde
6‘Bubble Gum’
(1 of 2 Bubble Gum)
Mt Baker Vapor
Refill bottle1223.811.1Ethyl butyrate105-54-4Ester
7.1Ethyl acetate141-78-6Ester
1.9Eugenol97-53-0Alcohol
1.1Limonene138-86-3Monoterpene
0.92-Methylbutyl acetate624-41-9Ester
0.8Cinnamaldehyde104-55-2Aldehyde
0.5Ethyl hexanoate6378-65-0Ester
7‘Menthol’
(2 of 4 Menthol)
NJOY
Disposable cartridge1821.519.7Menthol2216-51-5*Alcohol
0.9Menthone14073 -97-3*Ketone
0.6Neomenthol4919-01-0Alcohol
8‘French Vanilla’
(1 of 3 Vanilla)
Mt Baker Vapor
Refill bottle1218.88.4Ethyl vanillin121-32-4Aldehyde
6.1Vanillin121-33-5Aldehyde
4.1Maltol118-71-8Alcohol
9Cafe Mocha
(1 of 3 Coffee)
Halo
Refill bottle618.410.9Vanillin121-33-5Aldehyde
5.4Ethyl vanillin121-32-4Aldehyde
1.0Ethyl maltol4940-11-8Alcohol
0.7Piperonal120-57-0Aldehyde
10‘Menthol Ice’
(3 of 4 Menthol)
Halo
Refill bottle616.816.5Menthol2216-51-5*Alcohol
0.2Carvone6485-40-1*Ketone
0.1Vanillin121-33-5Aldehyde
11‘Grape’
(1 of 2 Grape)
Taste E-Liquid
Refill bottle2413.46.2Maltol118-71-8Alcohol
3.5Ethyl acetate141-78-6Ester
1.3Ethyl maltol4940-11-8Alcohol
1.0Methyl anthranilate134-20-3Ester
0.7Ethyl isovalerate108-64-5Ester
12‘Green Apple’
(1 of 2 Apple)
Mt Baker Vapor
Refill bottle1212.24.5(E)-2-Hexen-1-ol928-95-0Alcohol
4.3(3Z)-3-Hexen-1-ol928-96-1Alcohol
1.7Hexyl acetate142-92-7Ester
0.8Ethyl acetate141-78-6Ester
0.7Ethyl butyrate105-54-4Ester
13‘Longhorn’
(1 of 7 ‘Tobacco’)
Halo
Refill bottle610.48.4Benzyl alcohol100-51-6Alcohol
1.6Vanillin121-33-5Aldehyde
0.2Ethyl acetate141-78-6Ester
14‘555’
(2 of 7 ‘Tobacco’)
Mt Baker Vapor
Refill bottle129.37.1Vanillin121-33-5Aldehyde
1.7Maltol118-71-8Alcohol
0.3Ethyl vanillin121-32-4Aldehyde
15‘Grape’
(2 of 2 Grape)
Mt Baker Vapor
Refill bottle129.07.2Ethyl acetate141-78-6Ester
1.3Methyl anthranilate134-20-3Ester
0.6Ethyl butyrate105-54-4Ester
16‘Vanilla’
(2 of 3 Vanilla)
Rose City Vapors
Refill bottle127.54.9Ethyl vanillin121-32-4Aldehyde
1.7Ethyl maltol4940-11-8Alcohol
0.3Ethyl butyrate105-54-4Ester
17‘Bubblegum’
(2 of 2 Bubble Gum)
Viquid
Refill bottle127.52.9Limonene138-86-3Monoterpene
1.7Ethyl butyrate105-54-4ester
1.0Benzaldehyde100-52-7Aldehyde
0.62-Methylbutyl acetate624-41-9Ester
18‘Magnificent Menthol’
(4 of 4 Menthol)
BLU
Disposable cartridge22†7.15.7Menthol2216-51-5*Alcohol
0.6Menthone14 073 -97-3*Ketone
0.3Ethyl maltol4940-11-8Alcohol
19‘Java Jolt’
(2 of 3 Coffee)
BLU
Disposable cartridge22†6.74.7Maltol118-71-8Alcohol
1.5Ethyl maltol4940-11-8Alcohol
0.3Ethyl vanillin121-32-4Aldehyde
20‘First Step Tobacco’
(3 of 7 ‘Tobacco’)
Rose City Vapors
Refill bottle126.65.0Vanillin121-33-5Aldehyde
1.1Maltol118-71-8Alcohol
0.2Ethyl vanillin121-32-4Aldehyde
21‘Granny Smith Apple’
(2 of 2 Apple)
Taste E-Liquid
Refill bottle245.72.5Hexyl acetate142-92-7Ester
0.8Ethyl acetate141-78-6Ester
0.72-Methylbutyl acetate624-41-9Ester
22‘Vivid Vanilla’
(3 of 3 Vanilla)
BLU
Disposable cartridge22†4.72.6Ethyl vanillin121-32-4Aldehyde
1.5Vanillin121-33-5Aldehyde
0.3Benzyl alcohol100-51-6Alcohol
23‘Cherry’
(2 of 3 Cherry)
Taste E-Liquid
Refill bottle64.32.7Ethyl maltol4940-11-8Alcohol
0.9Benzaldehyde PG acetal2568-25-4Acetal
0.6Benzaldehyde100-52-7Aldehyde
24‘Belgium Cocoa’
(2 of 2 Chocolate/Cocoa)
Halo
Refill bottle63.72.3Vanillin121-33-5Aldehyde
0.8Maltol118-71-8Alcohol
0.62356-Tetramethylpyrazine1124-11-4Pyrazine
25‘Coffee’
(3 of 3 Coffee)
Mt Baker Vapor
Refill bottle122.62.3Benzyl alcohol100-51-6Alcohol
0.3Vanillin121-33-5Aldehyde
NAUnknown minor constituentsNAUnknown
26‘True Tobacco’
(4 of 7 ‘Tobacco’)
Taste E-Liquid
Refill bottle62.22.1Ethyl maltol4940-11-8Alcohol
0.1Vanillin121-33-5Aldehyde
NAUnknown minor constituentsNAUnknown
27‘Cherry Crush’
(3 of 3 Cherry)
BLU
Disposable cartridge24‡1.20.6Benzyl alcohol100-51-6Alcohol
0.3Piperonal120-57-0Aldehyde
0.3Vanillin121-33-5Aldehyde
28‘Torque 56’
(5 of 7 ‘Tobacco’)
Halo
Refill bottle61.20.8Benzyl alcohol100-51-6Alcohol
0.2β-Damascone23726 -91-2Ketone
0.1Ethyl butyrate105-54-4Ester
29‘Classic Tobacco’
(6 of 7 ‘Tobacco’)
BLU
Disposable cartridge22†∼0.10.1Benzyl alcohol100-51-6Alcohol
NAUnknown minor constituentsNAUnknown
30‘Traditional’
(7 of 7 ‘Tobacco’)
NJOY
Disposable cartridge18lowNAUnknown minor constituentsNAUnknown
  • Labelled Levels for Nicotine Given.

  • *Chirality of analytes not determined here. Most were probably L form.

  • †Based on labelled value for ‘mg nicotine per cartridge’ and fluid volume estimated here.

  • ‡Measured here.

  • CAS, Chemical Abstracts Service; NA, not applicable; PG, propylene glycol.