| US-based study ZRHM-REXA-08-US | ||||
| Measurement | Conventional cigarettes (n=32) | Smoking abstinence (n=9) | IQOS (n=47) | P values |
| Age (years) | 34±10 | 41±11 | 37±13 | 0.27 |
| Male | 20 (63%) | 7 (78%) | 28 (60%) | 0.59 |
| Smoking history | ||||
| 10–19 cig/day | 19 (59%) | 6 (67%) | 21 (45%) | 0.29 |
| >19 cig/day | 13 (41%) | 3 (33%) | 26 (55%) | |
| FEV1 (% predicted) | 97±14 | 96±11 | 93±13 | 0.46 |
| FEV1/FVC | 0.79±0.07 | 0.78±0.04 | 0.80±0.05 | 0.74 |
| WBC (GI/L) | 8.3±1.8 | 6.9±2.2 | 8.3±1.7 | 0.08 |
| CRP (mg/L) | 0.1 (0.1–0.2) | 0.1 (0.03–0.2) | 0.1 (0.1–0.3) | 0.11 |
IQOS, I-Quit-Ordinary-Smoking; CRP, C reactive protein; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; WBC, white blood cell count.