Table 1

Proposed maximum emission yield performance standard for combustible cigarettes and its relationship to test results published by Philip Morris International (PMI) and British American Tobacco (BAT) for tobacco heated products

Toxic emissionUnit of measure (applies to all values shown in this table)Test results
Combustible cigarette, mean values
Test results
Tobacco-heated stick (THS)
Proposed performance standard
(IARC carcinogen classification shown in brackets)*Per stickdu Maurier KSKentucky Reference Cigarette 3R4FMean valuesMean values2 SD from the highest THS value reported by either PMI or BATProposed maximum mean value†
Imperial Tobacco Canada18 PMI test14 BAT test15 PMI IQOS14 BAT glo15
1-Aminonaphthalene (3)ng13.521.617.60.0407nq0.02060.06
2-Aminonaphthalene (1)ng9.7516.213.20.0277nq0.018180.05
4-Aminobiphenyl (1)ng1.652.832.290.00958nq0.00280.01
Benzo[a]pyrene (1)ng25.311512.90.939nq0.15921.10
Formaldehyde (1)µg65.885.254.17.983.291.0088.99
Acetaldehyde (2B)µg11031641220021711115.7232.70
Acrolein (3)µg1751561579.632.221.40611.04
Crotonaldehyde (3)µg44.250.542<3.290.5676.58
Hydrogen cyanideµg296365343<4.37bdl8.74
Mercury (3)ng10.964.774.
Lead (2B)ng48.632.128.7<1.6211.60.46412.06
Cadmium (1)ng27892.9105<0.28bdl0.56
Nitric oxide (NO)µg11350449513.89.61.93415.73
Nitrogen oxides (NOx)µg56055514.112.91.88615.99
N-nitrosonornicotine (NNN) (1)ng28326310.224.7529.7
4-(Methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) (1)ng2642816.7524.7529.7
N-nitrosoanatabine (NAT) (3)ng2702681437.76.844.5
N-nitrosoanabasine (NAB) (3)ng30.224.11.924.70.785.48
Pyridine (2B)µg39.629.728.
Styrene (2B)µg26.515.416.11.05nq0.291.34
Hydroquinone (3)µg17789.
Resorcinol (3)µg3.591.791.57<0.055bdl0.11
Catechol (2B)µg21789.887.414.43.111.3615.75
Phenol (3)µg52.91413.51.120.1740.16981.29
Carbon monoxide (CO)mg16.730.2320.436nq0.16220.60
1,3-Butadiene (1)µg76.398.51080.342bdl0.06240.41
Isoprene (2B)µg4178948872.15nq0.4042.55
Acrylonitrile (2B)µg25.524.519.50.158bdl0.02440.18
Benzene (1)µg11581.178.60.544nq0.06240.61
Toluene (3)µg1991371311.82nq0.3262.15
  • Where no SD reported, to allow for uncertainty, proposed performance standard of the mean +2 SD is estimated at twice the highest mean value for THS reported by either PMI or BAT.

  • *IARC classification of carcinogens: Group 1, Carcinogenic to humans; Group 2A, Probably carcinogenic to humans; Group 2B, Possibly carcinogenic to humans; Group 3, Not classifiable as to its carcinogenicity to humans.

  • †Maximum mean value based on at least three replicates. This maximum value is equal to the mean +2 SD of the highest tobacco heat stick value reported by either PMI or BAT.

  • ‡No SD reported.

  • bdl, below detectable levels; IARC, International Agency for Research on Cancer; nq, not quantifiable.