HnB products assessed in the included studies
| HnB product and manufacturer | Release date, place | Description | Studies |
| Pax by Ploom (now PAX Labs) | 2012, USA | Loose-leaf tobacco and cannabis vaporiser. Loose tobacco is placed into a chamber and heated by an electrically powered element.40
A predecessor of Ploom Tech by JTI. | 40 |
| IQOS/THS 2.2 by PMI | 2014, Japan, Italy and Switzerland | IQOS includes a holder, a charger and tobacco sticks (Heets). A tobacco stick (about 320 mg) is inserted into the holder and the tobacco is heated with an electronically controlled heating blade which is inserted into tobacco plug. Operating heating temperature<350°C. A single use lasts 6 min or up to 14 puffs.61 Under ISO conditions, 12 puffs of the THS 2.2 yield 0.5 mg nicotine and 4.9 mg glycerol.44 | 5 21–27 29 31–35 39 41–45 48 49 |
| iFuse by BAT | 2015, Romania | iFuse includes an electronic vapour device with a rechargeable Li-ion battery and an integrated circuit power controller, onto which a cartomiser (Neopod) is attached. The disposable neopod comprises an atomiser, a liquid tank with 1.15 mL of non-flavoured nicotine liquid and a chamber containing a 130 mg tobacco plug. When the user presses a button, nicotine-containing vapour is produced, which is then drawn through the tobacco plug to absorb flavours. Before reaching the tobacco plug, the aerosol reaches an average maximum of <35°C.30 | 30 |
| Glo/THP 1.0 by BAT | 2016, Japan | Glo includes an electronic device with a rechargeable Li-ion battery and a heating chamber and tobacco sticks. A tobacco stick (about 260 mg) is heated in the heating chamber from the periphery. Operating heating temperature <250°C. Reaches operating temperature after 30–40 s and a single use lasts for another 3 min.28 | 5 28 29 36 41 51 |
| Ploom Tech/PNTV by JTI | 2016, Japan | PNTV includes a power supply unit, a cartridge with a heater and liquid and a capsule with tobacco blend. Generates a nicotine-free vapour by heating the unflavoured liquid; the vapour then passes through the tobacco capsule to absorb flavours and nicotine. Under HCI conditions, 50 puffs yield 1.10 mg nicotine.52 | 5 41 42 52 |
| Carbon-heated tobacco product (CHTP) by PMI | Not released | A specifically designed electric lighter lights the carbon heating source which then heats a tobacco plug. Under ISO conditions, 12 puffs of the CHTP yield 0.4 mg nicotine and 2 mg glycerol, 3 mg tar and 1 mg CO.47 A predecessor of TEEPS by PMI. | 47 |
| IQOS/THS 2.1 by PMI | Not released | THS 2.1 includes a holder, a charger and tobacco sticks. A tobacco stick is inserted into the holder and the tobacco is heated with an electronically controlled heating blade. Operating heating temperature<400°C. A single use lasts 6 min or up to 14 puffs. Under ISO conditions, 12 puffs of the THS 2.1 yield 0.3 mg nicotine and 5 mg glycerol.46 A predecessor of commercially available IQOS/THS 2.2. | 46 50 |
BAT, British American Tobacco; HnB, heat-not-burn tobacco product; ISO, International Organisation for Standardisation; PMI, Philip Morris International; PNTV, Prototype novel tobacco vapour product; JTI, Japan Tobacco International; LLTV, loose-leave tobacco vaporiser; PMI, Philip Morris International; THP, tobacco heating product; THS , tobacco heating system.