Relative nicotine delivery in mainstream HnB or e-cigarette aerosol in comparison to nicotine delivered to mainstream cigarette smoke
| Auer et al 21 2017* | Farsalinos et al 22 2018† | Bekki et al 23 2017 | Schaller et al 24 2016 | Schaller et al 25 2016 | Jaccard et al 26 2017 | Forster et al 36 2018 | Poynton et al 30 2017‡ | |
| Affiliation | University of Bern, Switzerland | University of Patras, Greece | National Institute of Public Health, Japan | PMI | PMI | PMI | BAT | BAT |
| Reference cigarette used | Lucky Strike Blue Lights | Marlboro Regular | 3R4F | 3R4F | 3R4F | 3R4F | 3R4F | 3R4F |
| Product | Nicotine levels, % (mg) | |||||||
| Reference cigarette (set as 100%) | 0.361 | 1.99 | 1.70 | 1.89 | 1.88 | 1.86 | 2.02 | 1.84 |
| IQOS | 83% (0.30) | 71% (1.41) | 65% (1.10) | 70% (1.32) | 73% (1.38) | 61% (1.14) | 57% (1.16) | – |
| Glo | – | – | – | – | – | – | 23% (0.462) | – |
| iFuse | – | – | – | – | – | – | – | 19% (2.56/0.358) |
| Cigalike e-cigarette | – | 43% (0.86) | – | – | – | – | – | – |
| Second-generation pen-style e-cigarette | – | 87% (1.73) | – | – | – | – | – | 27% (3.57/0.500) |
| Third-generation tank-style e-cigarette | – | 92% (1.84) | – | – | – | – | – | – |
*Provided nicotine values under ISO machine puffing regimen.
† Nicotine levels for HnB and e-cigarettes provided under 4 s puffing regimen.
‡ Nicotine levels were provided for 100 puff blocks under 3 s puffing regimen; nicotine level for 14 puffs was calculated by multiplying the nicotine level for 100 puffs by 0.14.
–, Not measured; BAT, British American Tobacco; PMI, Philip Morris International.