Exploratory unadjusted and adjusted ORs of wheezing and related respiratory symptoms associated with vaping and smoking due to prolonged effect of past smoking
| Wheezing and other related respiratory symptoms | Current vapers who were ex-smokers vs never-smokers | Current vapers who never smoked vs never-smokers | Current smokers vs never-smokers | Current vapers who were ex-smokers vs ex-smokers | Ex-smokers vs never-smokers | |||||
| Unadjusted OR (95% CI) | Adjusted OR (95% CI) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | |
| Ever had wheezing or whistling in chest at any time in past | 2.78 (2.25 to 3.43) | 2.27 (1.71 to 3.01) | 2.00 (1.29 to 3.08) | 1.42 (0.75 to 2.70) | 3.73 (3.37 to 4.12) | 3.03 (2.63 to 3.50) | 1.78 (1.46 to 2.18) | 1.53 (1.18 to 1.97) | 1.56 (1.41 to 1.72) | 1.49 (1.31 to 1.70) |
| Wheezing or whistling in chest in past 12 months | 2.67 (2.17 to 3.28) | 2.21 (1.68 to 2.91) | 1.96 (1.32 to 2.91) | 1.49 (0.84 to 2.67) | 4.00 (3.62 to 4.43) | 3.33 (2.87 to 3.85) | 1.74 (1.44 to 2.12) | 1.54 (1.20 to 1.98) | 1.53 (1.39 to 1.69) | 1.43 (1.26 to 1.63) |
| Number of wheezing attacks more than 12 in past 12 months | 2.42 (1.84 to 3.18) | 2.21 (1.56 to 3.15) | 1.77 (1.18 to 2.67) | 1.38 (0.73 to 2.62) | 4.47 (3.95 to 5.06) | 3.95 (3.36 to 4.65) | 1.70 (1.31 to 2.21) | 1.57 (1.13 to 2.17) | 1.42 (1.26 to 1.62) | 1.41 (1.22 to 1.64) |
| One or more nights per week had sleep disturbed due to wheezing | 2.37 (1.82 to 3.08) | 2.19 (1.57 to 3.05) | 1.84 (1.17 to 2.90) | 1.52 (0.79 to 2.97) | 4.43 (3.92 to 5.00) | 3.87 (3.29 to 4.55) | 1.67 (1.29 to 2.16) | 1.56 (1.14 to 2.14) | 1.42 (1.25 to 1.61) | 1.40 (1.20 to 1.63) |
| Speech limited to only one or two words between breaths due to wheezing in past 12 months | 2.43 (1.85 to 3.19) | 2.28 (1.63 to 3.20) | 1.88 (1.22 to 2.90) | 1.64 (0.91 to 2.96) | 4.50 (3.97 to 5.09) | 3.96 (3.32 to 4.71) | 1.71 (1.32 to 2.22) | 1.63 (1.19 to 2.24) | 1.42 (1.25 to 1.61) | 1.40 (1.20 to 1.64) |
| Chest has sounded wheezy during or after exercise | 2.10 (1.56 to 2.84) | 1.50 (1.07 to 2.10) | 1.80 (1.09 to 2.99) | 0.85 (0.41 to 1.78) | 3.30 (2.95 to 3.70) | 2.32 (2.01 to 2.69) | 1.67 (1.23 to 2.27) | 1.22 (0.88 to 1.70) | 1.26 (1.09 to 1.45) | 1.23 (1.03 to 1.47) |
| Dry cough at night not associated with a cold or chest infection | 1.72 (1.29 to 2.29) | 1.54 (1.12 to 2.11) | 2.10 (1.30 to 3.39) | 1.59 (0.84 to 3.00) | 3.63 (3.27 to 4.03) | 2.61 (2.31 to 2.94) | 1.35 (1.00 to 1.82) | 1.22 (0.88 to 1.69) | 1.28 (1.13 to 1.44) | 1.26 (1.09 to 1.46) |
The adjusted ORs controlled the effect of age categories, sex, race/ethnicity, income level, body mass index categories, duration of electronic-cigarette use, self-reported asthma, self-perception of physical health, self-perception of mental health and secondhand smoke exposure.