Likelihood of conditional exclusion of people with MHDs by the class of medication unadjusted and adjusted for publication year of smoking cessation RCTs
Trial characteristics | Unadjusted | Adjusted | ||
OR (95% CI) | P value | OR (95% CI) | P value | |
Publication year | 0.95 (0.92 to 0.99) | 0.008 | 0.95 (0.89 to 1.00) | 0.051 |
Class of medication | ||||
NRT | 1.00 | – | 1.00 | – |
Antidepressants | 2.38 (1.06 to 5.33) | 0.035 | 3.33 (1.38 to 8.01) | 0.007 |
nAChR partial agonists | 1.09 (0.44 to 2.71) | 0.856 | 1.87 (0.65 to 5.38) | 0.245 |
Others | 0.38 (0.13 to 1.08) | 0.070 | 0.39 (0.13 to 1.16) | 0.092 |
Base compared to NRTs. Logistic regression.
MHDs, mental health disorders; nAChR, nicotinic acetylcholine receptor; NRT, nicotine replacement therapy; RCTs, randomised controlled trials.