Table 4

Likelihood of conditional exclusion of people with MHDs by the class of medication unadjusted and adjusted for publication year of smoking cessation RCTs

Trial characteristicsUnadjustedAdjusted
OR (95% CI)P valueOR (95% CI)P value
Publication year0.95 (0.92 to 0.99)0.0080.95 (0.89 to 1.00)0.051
Class of medication
 NRT1.001.00
 Antidepressants2.38 (1.06 to 5.33)0.0353.33 (1.38 to 8.01)0.007
 nAChR partial agonists1.09 (0.44 to 2.71)0.8561.87 (0.65 to 5.38)0.245
 Others0.38 (0.13 to 1.08)0.0700.39 (0.13 to 1.16)0.092
  • Base compared to NRTs. Logistic regression.

  • MHDs, mental health disorders; nAChR, nicotinic acetylcholine receptor; NRT, nicotine replacement therapy; RCTs, randomised controlled trials.