Table 1

Ten frequently added flavouring ingredients in waterpipe tobacco registered in EU-CEG (March 2019, the Netherlands) and anethole.

Flavouring agentCAS no.Prevalence (%)Median concentration (mg/g)Flavour descriptionSmoke tasteGHS code
1Vanillin121-33-5590.31Sweet, powerful, creamy, vanilla-likeSweet vanilla; used widely in tobacco flavours at levels of 25 ppm up to add sweetnessH317, H319
2Ethyl Vanillin121-32-4470.02Intense, sweet, vanilla-like odour; creamy, vanilla tasteSweet, strong vanilla notes; useful for adding sweetness over a wide range of levelsH302, H315, H319, H335, H412
3Dihydrocoumarin119-84-6410.001Very sweet, nut-like, hay-like, coumarin-tobacco like odourNutty, hay, honey, spicy; sweet coumarin-likeH302, H317
4Ethyl Butyrate105-54-4401.24Ethereal, fruity with buttery-pineapple-banana, ripe fruit and juicy notesSweet, fruity, winey, excellent in any fruit or wine flavour for tobaccoH226
5Ethyl Acetate141-78-6340.49Ethereal, sharp, wine-brandy-likeWeak fruity, chemical; not important as a tobacco flavourH225, H319, H336
6Ethyl-2-methylbutyrate7452-79-1310.54Strong, green, fruity, apple with strawberry notesGreen apple, winey-fruityH226
7Maltol118-71-8270.22Sweet, fruity, berry, strawberry, caramellicSweet, flue-cured; tends to fade somewhat on ageing; excellent tobacco flavour; used in caramel, nut, brown sugar maple and flue-cured flavoursH302
8Isoamyl Acetate123-92-2251.10Sweet, fruity, banana, pear odour and tasteWeak, sweet, bananaH226
9Menthol2216-51-5250.76String trigeminal cooling sensation with a slight mint noteNo description availableH315, H319
10Benzyl Alcohol100-51-6251.26Faint, sweet, almond fruity, somewhat chemicalVery weak cherry-floral, smoothing; primarily used as a cosolvent for highly water insoluble materials such as sclareolide and anise oilsH302, H332
11Anethole4180-23-8112.25Sweet, herbaceous, anise (artificial Licorice) odour and tasteSweet, aniseH317
  • This table contains the name of the flavour ingredient, the frequency of addition in the registered waterpipe tobacco products and median concentration per product. Flavour and smoke taste descriptions were collected form the Leffingwell database.29 Flavour descriptions are based on the individual flavourings. The smoke taste is the taste of a flavouring in smoke observed after combustion of tobacco containing the flavouring. Hazard statements of the Globally Harmonized System of Classification and Labeling of Chemicals (GHS codes) were derived from PubChem.

  • EU-CEG, European Common Entry Gate.