Effect of e-liquid flavouring on all outcomes
| Linear regressions (continuous outcomes) | ||||
| Outcome | Unadjusted | Adjusted | ||
| b (95% CI) | P value | b (95% CI) | P value | |
| Cigarette craving (average) | 0.18 (−0.44 to 0.79) | 0.568 | 0.18 (−0.45 to 0.81) | 0.573 |
| Cigarette craving (peak) | −0.12 (−0.59 to 0.35) | 0.616 | −0.02 (−0.50 to 0.46) | 0.934 |
| Cue-elicited cigarette craving | −0.21 (−3.86 to 3.43) | 0.907 | 0.78 (−3.04 to 4.60) | 0.685 |
| Enjoyment of e-cigarette | 0.33 (−0.07 to 0.74) | 0.107 | 0.30 (−0.14 to 0.74) | 0.177 |
| Ease of transitioning to using e-cigarette | −0.19 (−0.66 to 0.28) | 0.422 | −0.20 (−0.69 to 0.29) | 0.423 |
| Intentions to continue using e-cigarette | −0.17 (−0.60 to 0.27) | 0.446 | −0.38 (−0.80 to −0.05) | 0.085 |
| Intentions to quit smoking | 0.21 (−0.28 to 0.71) | 0.393 | −0.05 (−0.48 to 0.39) | 0.830 |
| Motivation to quit smoking | 0.12 (−0.74 to 0.98) | 0.784 | −0.30 (−1.07 to 0.48) | 0.449 |
| Sweet food craving (average) | 0.40 (−0.13 to 0.94) | – | 0.37 (−0.18 to 0.92) | – |
| Sweet food craving (peak) | 0.57 (−0.01 to 1.15) | – | 0.66 (0.05 to 1.27) | – |
| Savoury food craving (average) | −0.06 (−0.57 to 0.45) | – | −0.03 (−0.58 to 0.52) | – |
| Savoury food craving (peak) | −0.10 (−0.55 to 0.36) | – | −0.05 (−0.54 to 0.43) | – |
| Logistic regressions (binary outcomes) | ||||
| Outcome | Unadjusted | Adjusted | ||
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Smoking lapse occurrence | 0.83 (0.25 to 2.73) | 0.763 | 1.01 (0.29 to 3.55) | 0.985 |
| Return to smoking | 0.70 (0.27 to 1.83) | 0.464 | 1.19 (0.40 to 3.59) | 0.755 |
| Continuation of use (past week) | 1.54 (0.24 to 9.71) | 0.647 | 1.15 (0.15 to 8.64) | 0.895 |
| Continuation of use (future) | 4.32 (0.46 to 40.35) | 0.200 | 3.32 (0.31 to 35.70) | 0.321 |
N=84. Condition code: unflavoured=0, flavoured=1. Unstandardised b coefficients.
Adjusted: adjusted for age, gender, cigarettes per day, cigarette dependence and quit motivation (baseline characteristics).
P values are not reported for exploratory analyses as (by definition) there was no hypothesis testing.
Primary measures: cigarette craving (average): mean average daily cigarette craving score (0 ‘strongly disagree’ to 7 ‘strongly agree’); cigarette craving (peak): highest daily cigarette craving score; cue-elicited cigarette craving: Questionnaire of Smoking Urges-Brief change scores (post-task minus pre-task).
Secondary measures: enjoyment of e-cigarette (1 ‘not at all’ to 5 ‘a great deal’), ease of transitioning to using e-cigarette (1 ‘very difficult’ to 5 ‘very easy’), intentions to continue using e-cigarette and intentions to quit smoking (1 ‘definitely not’ to 5 ‘definitely’), motivation to quit smoking (Readiness to Quit Ladder), and sweet and savoury food cravings (1 ‘strongly disagree’ to 7 ‘strongly agree’).
Binary outcomes were scored as 0=no and 1=yes.
e-cigarette, electronic cigarette.