High dependence | Low dependence | |||||
+F+H | +F-H | −F−H | +F+H | +F-H | −F−H | |
Topography outcomes (mean (SD)) | ||||||
Average flow rate (L/min) | 14.2 (5.3) | 17.0 (5.3) | 17.7 (4.8) | 15.5 (5.0) | 15.1 (4.3) | 16.9 (4.5) |
Average interpuff interval (s) | 40.1 (29.1) | 35.8 (29.5) | 33.0 (28.0) | 44.4 (26.3) | 41.5 (25.2) | 44.6 (28.4) |
Average puff duration () | 2.4 (1.0) | 3.3 (1.5) | 3.4 (1.2) | 3.0 (1.0) | 3.2 (1.3) | 3.4 (1.2) |
Average puff volume (L) | 0.6 (0.4) | 1.0 (0.5) | 1.0 (0.5) | 0.8 (0.4) | 0.8 (0.4) | 1.0 (0.5) |
Maximum puff volume | 1.3 (0.8) | 1.7 (0.8) | 2.1 (0.9) | 1.6 (0.7) | 1.9 (2.0) | 2.4 (2.2) |
Total puffing time (min) | 3.0 (2.8) | 3.0 (2.2) | 4.7 (3.4) | 3.4 (2.2) | 3.5 (2.3) | 3.7 (2.4) |
Total smoking time (min) | 35.4 (16.5) | 29.9 (18.1) | 39.4 (17.0) | 43.1 (15.2) | 40.6 (13.1) | 41.4 (17.0) |
Total inhaled volume (L) | 46.0 (57.1) | 50.5 (41.2) | 81.8 (60.2) | 54.3 (42.7) | 52.3 (35.6) | 65.0 (47.2) |
Total no of puffs | 72.4 (66.9) | 56.2 (51.7) | 88.1 (71.7) | 66.6 (40.0) | 62.4 (31.2) | 67.5 (47.7) |
Biomarkers of exposure (mean (SD)) | ||||||
Plasma nicotine boost (ng/mL) | 13.0 (27.6) | 4.4 (5.4) | 7.0 (6.5) | 11.6 (9.4) | 7.0 (5.4) | 6.7 (6.7) |
eCO boost (ppm) | 27.0 (38.1) | 41.9 (41.9) | 69.5 (55.7) | 36.0 (29.1) | 41.8 (36.4) | 45.8 (42.8) |
Subjective drug liking (mean (SD)) | ||||||
Enjoyed product | 51.7 (28.3) | 50.4 (36.8) | 39.4 (29.3) | 63.6 (28.4) | 50.1 (27.9) | 41.8 (29.2) |
Interested in using product in future | 50.3 (33.5) | 46.2 (34.5) | 39.4 (29.9) | 59.2 (33.2) | 44.5 (26.4) | 33.0 (30.5) |
Liked product | 53.2 (28.4) | 49.7 (36.4) | 40.7 (29.1) | 62.4 (29.6) | 50.6 (28.6) | 38.5 (29.1) |
Found product pleasurable | 53.2 (28.7) | 50.3 (34.4) | 42.8 (29.2) | 61.5 (28.0) | 49.6 (26.7) | 41.1 (28.8) |
Found product satisfying | 52.4 (30.8) | 48.7 (34.2) | 43.0 (30.3) | 62.0 (28.3) | 49.0 (28.4) | 42.1 (29.1) |
Willingness to use product in future | 55.9 (35.0) | 53.1 (34.7) | 44.8 (32.7) | 63.3 (33.5) | 49.8 (27.2) | 39.8 (31.9) |
Behavioural intentions (% likely or extremely likely) | ||||||
Try product again | 59.4 | 53.9 | 38.7 | 72.9 | 37.5 | 27.3 |
Pay to smoke product in hookah lounge/bar | 53.1 | 42.3 | 29.0 | 56.3 | 27.5 | 19.3 |
Purchase product for personal use | 40.6 | 30.8 | 27.4 | 41.7 | 17.5 | 11.4 |
Use product regularly | 31.3 | 19.2 | 12.9 | 29.2 | 20.0 | 6.8 |
eCO, expired carbon monoxide.