Table 2

Outcomes measured in heated tobacco product clinical trials

Outcome typeNumber of outcomesNumber of trials
MeasuredReported in ≥1 trialMeasured outcomeReported data on outcome
Biomarker of exposure25253228
Biomarker of exposure*222824
Biomarker of potential harm1251042119
Nicotine pharmacokinetics18161716
Subjective effects (questionnaire)20172822
Other measures15122218
Safety profile982423
  • *Two biomarkers of exposure were also measured as biomarkers of potential harm in one trial.