Outcomes measured in heated tobacco product clinical trials
| Outcome type | Number of outcomes | Number of trials | ||
| Measured | Reported in ≥1 trial | Measured outcome | Reported data on outcome | |
| Biomarker of exposure | 25 | 25 | 32 | 28 |
| Biomarker of exposure* | 2 | 2 | 28 | 24 |
| Biomarker of potential harm | 125 | 104 | 21 | 19 |
| Nicotine pharmacokinetics | 18 | 16 | 17 | 16 |
| Subjective effects (questionnaire) | 20 | 17 | 28 | 22 |
| Other measures | 15 | 12 | 22 | 18 |
| Safety profile | 9 | 8 | 24 | 23 |
*Two biomarkers of exposure were also measured as biomarkers of potential harm in one trial.