Table 2

Proposal for a list of allowed flavourings in e-cigarette e-liquids

CAS NoFlavouring nameFlavour descriptionAssociation with tobacco
35044-68-9beta-DamasconeComplex odour of blackcurrant, plum, rose, honey and tobaccoTobacco-like flavour
23726-91-2(E)-beta-DamasconeComplex odour of blackcurrant, plum, rose, honey and tobaccoTobacco-like flavour
23726-92-3(Z)-beta-DamasconeComplex odour of blackcurrant, plum, rose, honey and tobaccoTobacco-like flavour
23696-85-7DamascenoneFruity floral with apple-plum-raisin-prune, tea, rose, tobacco notesTobacco-like flavour
23726-93-4(E)-beta-DamascenoneFruity floral with apple-plum-raisin-prune, tea, rose, tobacco notesTobacco-like flavour
1125-21-9KetoisophoroneTobacco-like, hay straw, tea notes, honeyTobacco-like flavour
4883-60-72-Hydroxy-3,5,5-trimethyl-2-cyclohexenoneSweet, musty tea, caramellic odour; musty, tea, nutty, tobacco tasteTobacco-like flavour
536-78-73-EthylpyridineStrong tobacco, roasted, nutty, smoky notes odour; tobacco-like flavourTobacco-like flavour
350-03-83-AcetylpyridineStrong, burnt roasted, nutty, cigar tobacco-likeTobacco-like flavour
91-10-12,6-DimethoxyphenolPhenolic-woody-medicinal, smoky odour; a tarry, spicy, smoky (bacon) tasteAttribute of tobacco aroma
67-47-05-(Hydroxymethyl)-2-furfuralHerbaceous winey hay-like odour, sweet herbaceous hay and tobacco-like tasteTobacco-like flavour
591-12-8alpha-Angelica lactoneSweet, bread, molasses, coumarin, tobacco odour; nut-like tasteTobacco-like flavour
503-74-2Isovaleric acidVery sour, ’sweaty’, cheesy, odour; fruity on dilutionAttribute of tobacco aroma
1139-30-6(−)-Caryophyllene oxideDry, woody, faint cedar, tobacco-like notesTobacco-like flavour
3738-00-9AmbroxideIntense velvety ambergris notesPresent in tobacco smoke
564-20-5(3aR)-(+)-SclareolideCedary; impact compound of certain tobaccos; fish and berry flavour improverTobacco-like flavour

  • Terms associated with tobacco or tobacco smoke are indicated in bold.