Table 3

Statistical analysis of the impact of puffing parameters and IQOS flavour on IQOS nicotine and carbonyl emissions

Tobacco productNicotine (mg/item)Formaldehyde (µg/item)Acetaldehyde (µg/item)Acrolein (µg/item)
IQOSCigarette (3R4F)IQOSCigarette (3R4F)IQOSCigarette (3R4F)IQOSCigarette (3R4F)
Puff duration (s)0.35±0.07***0.35±0.13*3.00±1.853.86±16.70−2.59±7.15164.60±555.601.48±0.7739.48±18.56
Number of puffs (/session)0.06±0.02**−0.01±0.020.35±0.51−0.58 ±2.642.09±1.95−9.51±87.900.44±0.220.00±2.90
Flow rate (L/min)0.68±0.16***2.10±0.20***3.55±4.2548.40±26.4637.60±16.39*1507.31±879.903.40±1.77133.20±29.42**
IQOS flavour/cigarette type (categorical)******
Affiliation (categorical)*****
  • Data on combustible cigarettes were analysed for comparison.

  • B (unstandardised regression coefficient)±SE, statistical significance at: *p<0.05; **p<0.01; ***p<0.001.