Table 2

Nicotine yield (mean±SD) in IQOS-R aerosols under different puffing regimes

ReferenceAffiliation/fundingPuffing regime (PR)Puff duration (s)Interpuff interval (s)Puff volume (mL)Nicotine yield (mg/stick)
Schaller et al 41 PMIHCI2.030551.32±0.16
ISO2.060350.49±0.08
PR12.425601.64±0.22
PR22.425801.8±0.41
PR34.5221102.19±0.43
PR42.430400.76±0.19
PR52.430801.13±0.11
Schaller et al 42 PMIHCI2.030551.38±0.20
Jaccard et al 9 PMIHCI2.030551.14±0.03
Poget et al 43 PMIHCI2.030551.36±0.09
ISO2.060350.49±0.04
PR12.425601.64±0.10
PR22.425801.8±0.19
PR34.5221102.19±0.20
PR42.430400.76±0.09
PR52.430801.13±0.05
Ibañez et al 44 PMIHCI2.030551.15±0.02
Gasparyan et al 110 BATHCI2.030551.23±0.05
Auer et al 36 IndISO2.060350.30±0.21
Bekki et al 51 IndHCI2.030551.10
Farsalinos et al 45 IndHCI2.030551.40±0.16
PR64.030551.41±0.08
Farsalinos et al 52 IndHCI2.030551.20
PR73.030801.31
PR83.025901.60
Leigh et al 50 IndHCI2.030551.40±0.20
Mallock et al 53 IndHCI2.030551.1±0.10
Uchiyama et al 54 IndHCI2.030551.2±0.13
ISO2.060350.40±0.07
Cancelada et al 46 IndHCI2.030550.99±0.10
Li et al 55 IndHCI2.030551.35±0.07
ISO2.060350.50±0.03
Meehan-Atrash et al 56 IndPR93.030551.22±0.12
Salman et al 47 IndHCI2.030551.50±0.20
ISO2.060350.77±0.06
Bitzer et al 48 IndPR102.530751.47±0.12
Wang et al 49 IndISO2.060350.55±0.01
Dusautoir et al 57 IndHCI2.030550.76
Perezhogina et al 58 IndHCI2.030551.10±0.03
  • BAT, British American Tobacco; HCI, Health Canada Intense puffing regime; Ind, independent; IQOS-R, IQOS regular; ISO, International Organization for Standardization; PMI, Philip Morris International.