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Prediction Model for Low Birth Weight and its Validation

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Abstract

Objective

To evaluate the factors associated with low birth weight (LBW) and to formulate a scale to predict the probability of having a LBW infant.

Methods

This hospital based case–control study was conducted in a tertiary care university hospital in North India. The study included 250 LBW neonates and 250 neonates with birth weight ≥2,500 g. Data were collected by interviewing mothers using pre-designed structured questionnaire and from hospital records.

Results

Factors significantly associated with LBW were inadequate weight gain by the mother during pregnancy (<8.9 kg), inadequate proteins in diet (<47 g/d), previous preterm baby, previous LBW baby, anemic mother and passive smoking. The prediction model made on these six variables has a sensitivity of 71.6 %, specificity 67.0 %, positive LR 2.17 and negative LR of 0.42 for a cut-off score of ≥29.25. On validation, it has a sensitivity of 72 % and specificity of 64 %.

Conclusions

It is possible to predict LBW using a prediction model based on significant risk factors associated with LBW.

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Contributions

AS, SA, HC and KA: Conception and design, analysis and interpretation of data, drafting the manuscript, critical revision of the manuscript for intellectual content and final approval of the version to be published; RP: Statistical analysis.

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Correspondence to Harish Chellani.

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Singh, A., Arya, S., Chellani, H. et al. Prediction Model for Low Birth Weight and its Validation. Indian J Pediatr 81, 24–28 (2014). https://doi.org/10.1007/s12098-013-1161-1

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  • DOI: https://doi.org/10.1007/s12098-013-1161-1

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