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2024, International Review of NeurobiologyDifferences in mechanisms underlying reinstatement of cigarette smoke extract- and nicotine-seeking behavior in rats
2020, NeuropharmacologyCitation Excerpt :These may include MAO inhibitors, which are present in CSE and which can create a distinct pattern of neuronal activation from that of nicotine alone (Arnold et al., 2014). Other aqueous constituents that are likely present in CSE include acetaldehyde and other tobacco alkaloids, constituents that have also been shown to have a pharmacologically relevant contribution to the addictive profile of tobacco (Myers et al., 1982; Arizzi et al., 2003; Belluzzi et al., 2005; Clemens et al., 2009). Future studies may examine the role of these individual constituents in modifying sensitivity to nicotine- and cue-induced drug-seeking behavior.
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