Abstract
Tailored health interventions can be more effective in eliciting positive behavior change than generic interventions, but the underlying neural mechanisms are not yet understood. Here, 91 smokers participated in a functional magnetic resonance imaging session and a tailored smoking-cessation program. We found that increases in activation in self-related processing regions, particularly dorsomedial prefrontal cortex, to tailored messages predicted quitting during a 4-month follow-up.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
Purchase on Springer Link
Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Lancaster, T. & Stead, L.F. Cochrane Database Syst. Rev. CD001118 (2005).
Brug, J., Campbell, M. & van Assema, P. Patient Educ. Couns. 36, 145–156 (1999).
Dijkstra, A. Health Educ. Res. 20, 527–539 (2005).
Strecher, V. Annu. Rev. Clin. Psychol. 3, 53–76 (2007).
Symons, C.S. & Johnson, B.T. Psychol. Bull. 121, 371–394 (1997).
Northoff, G. & Bermpohl, F. Trends Cogn. Sci. 8, 102–107 (2004).
Northoff, G. et al. Neuroimage 31, 440–457 (2006).
Chua, H.F., Liberzon, I., Welsh, R.C. & Strecher, V.J. Biol. Psychiatry 65, 165–168 (2009).
Strecher, V.J. et al. Am. J. Prev. Med. 34, 373–381 (2008).
Velicer, W.F. & Prochaska, J.O. Addict. Behav. 29, 51–60 (2004).
Schmitz, T.W. & Johnson, S.C. Neuroimage 30, 1050–1058 (2006).
van der Meer, L., Costafreda, S., Aleman, A. & David, A.S. Neurosci. Biobehav. Rev. 34, 935–946 (2010).
Acknowledgements
This work was supported by National Institute of Drug Abuse grant R21-DA024429-01 to H.F.C. and V.J.S.
Author information
Authors and Affiliations
Contributions
H.F.C. performed all aspects of this study, including experimental design, data collection, analyses, interpretation and manuscript preparation. S.S.H. and A.J.J. assisted in the data analyses, interpretation and manuscript preparation. T.A.P., R.C.W. and I.L. contributed to the experiment design, data interpretation and manuscript preparation. V.J.S. contributed to the experimental design.
Corresponding author
Ethics declarations
Competing interests
Victor J Strecher is the Chief Visionary Officer and Founder of HealthMedia, a company that develops and licenses computer-tailored health promotion, disease prevention and disease management tools.
Supplementary information
Supplementary Text and Figures
Supplementary Figures 1–4, Supplementary Tables 1–5, Supplementary Results and Supplementary Methods (PDF 308 kb)
Rights and permissions
About this article
Cite this article
Chua, H., Ho, S., Jasinska, A. et al. Self-related neural response to tailored smoking-cessation messages predicts quitting. Nat Neurosci 14, 426–427 (2011). https://doi.org/10.1038/nn.2761
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/nn.2761
This article is cited by
-
A multiscale modeling framework to study the interdependence of brain, behavior, and pandemic
Nonlinear Dynamics (2023)
-
Brain Systems Underlying Fundamental Motivations of Human Social Conformity
Neuroscience Bulletin (2023)
-
The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex
Neuropsychopharmacology (2022)
-
Physiology-based personalization of persuasive technology: a user modeling perspective
User Modeling and User-Adapted Interaction (2022)
-
A methodological checklist for fMRI drug cue reactivity studies: development and expert consensus
Nature Protocols (2022)