Most published research findings are false-but a little replication goes a long way

Ramal Moonesinghe; Muin J Khoury; A Cecile J W Janssens

doi:10.1371/journal.pmed.0040028

Most published research findings are false-but a little replication goes a long way

PLoS Med. 2007 Feb;4(2):e28. doi: 10.1371/journal.pmed.0040028.

Authors

Ramal Moonesinghe¹, Muin J Khoury, A Cecile J W Janssens

Affiliation

¹ National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America. RMoonesinghe@CDC.gov

Abstract

While the authors agree with John Ioannidis that "most research findings are false," here they show that replication of research findings enhances the positive predictive value of research findings being true.

MeSH terms

Data Interpretation, Statistical*
Humans
Models, Statistical
Predictive Value of Tests
Publishing*
Research Design*