This was an exploratory study of precessation interaction between 21 smokers and their partners enrolled in a partner support smoking treatment program. The aim was to identify the partner interactions and proposed quitting strategies that were associated with cessation. Significant results (p less than .05) and trends (p less than .10) were reported. Both smoker and partner interactions predicted cessation. Failure to quit was predicted by smokers' negative behavior (prosmoking statements, interrupting the partner, and criticism/rejection of help) and by partners' suggestion to disengage from the quitting process. Partner's suggestion to disengage may be a reaction to the smokers' negative behavior because it was positively correlated with it. Successful quitters and their partners proposed more self-help strategies than did nonquitters and their partners. Nonquitters proposed more cooperative strategies than did successful quitters. Thus, suggesting strategies that encourage autonomy and self-mastery, rather than dependence on another person, may lead to more positive outcomes.